Meta-Analysis
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. Sep 6, 2016; 5(5): 482-488
Published online Sep 6, 2016. doi: 10.5527/wjn.v5.i5.482
Association of blood transfusion with acute kidney injury after transcatheter aortic valve replacement: A meta-analysis
Charat Thongprayoon, Wisit Cheungpasitporn, Erin A Gillaspie, Kevin L Greason, Kianoush B Kashani
Charat Thongprayoon, Wisit Cheungpasitporn, Kianoush B Kashani, Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN 55905, United States
Erin A Gillaspie, Kevin L Greason, Division of Cardiovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, MN 55905, United States
Kianoush B Kashani, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN 55905, United States
Author contributions: Thongprayoon C and Cheungpasitporn W contributed equally to this work; Thongprayoon C and Cheungpasitporn W contributed to performing the search, analysis and interpretation of data, analysis of data and final approval of the version to be published; Gillaspie EA contributed to critical revising of the intellectual content and final approval of the version to be published; Greason KL contributed to critical revising of the intellectual content and final approval of the version to be published; Kashani KB contributed to concept and design, critical revising of the intellectual content and final approval of the version to be published.
Conflict-of-interest statement: All authors report no conflicts-of-interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Kianoush B Kashani, MD, Assistant Professor, Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States. kashani.kianoush@mayo.edu
Telephone: +1-507-2667093 Fax: +1-507-2667891
Received: March 19, 2016
Peer-review started: March 22, 2016
First decision: April 20, 2016
Revised: April 23, 2016
Accepted: June 27, 2016
Article in press: June 29, 2016
Published online: September 6, 2016
Processing time: 166 Days and 3.9 Hours
Core Tip

Core tip: We performed this meta-analysis to assess the impact of periprocedural red blood cell (RBC) transfusion on the risk of acute kidney injury (AKI) after transcatheter aortic valve replacement (TAVR). We verified a significant association between peri-procedural RBC transfusion and AKI after a TAVR with an overall 1.95-fold increased risk of AKI compared to those who did not receive transfusion. This study highlights the importance of vigilance when considering transfusions and should impact the clinical management of the high-risk group of patients undergoing TAVR.