Review
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. Nov 6, 2015; 4(5): 500-510
Published online Nov 6, 2015. doi: 10.5527/wjn.v4.i5.500
Pre-treatment considerations in childhood hypertension due to chronic kidney disease
Wasiu Adekunle Olowu
Wasiu Adekunle Olowu, Paediatric Nephrology and Hypertension Unit, Obafemi Awolowo University Teaching Hospitals Complex, PMB 5538, Ile-Ife, State of Osun, Nigeria
Author contributions: Olowu WA is the sole author of this article.
Conflict-of-interest statement: Author declares no conflict of interest for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Wasiu Adekunle Olowu, MBBS, FMCPaed, Professor of Paediatric Nephrology and Hypertension, Head, Paediatric Nephrology and Hypertension Unit, Obafemi Awolowo University Teaching Hospitals Complex, PMB 5538, Ile-Ife, State of Osun, Nigeria. yetundeolowu@yahoo.com
Telephone: +234-80-37218742 Fax: +234-80-36230141
Received: May 27, 2015
Peer-review started: May 29, 2015
First decision: August 4, 2015
Revised: August 30, 2015
Accepted: October 1, 2015
Article in press: October 8, 2015
Published online: November 6, 2015
Processing time: 169 Days and 8.8 Hours
Core Tip

Core tip: Hypertension (HTN) is often difficult to control in chronic kidney disease (CKD). Failure to achieve the desired therapeutic BP target in the hypertensive CKD child could be due to comorbidities and toxic effects of HTN promoting medications. So, before starting or altering anti-hypertensive medications, it is important that patients are evaluated for the roles that HTN promoting medications and co-morbidities like chronic anaemia, hyperphosphataemia, progressive tunica media calcifications, and serum parathyroid hormone levels that are well above the acceptable limits for CKD stage could be playing in the entire process. Ways of solving this important clinical problem are the focus of this article.