Editorial
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. Mar 25, 2025; 14(1): 99120
Published online Mar 25, 2025. doi: 10.5527/wjn.v14.i1.99120
Link between obstructive uropathy and acute kidney injury
Guido Gembillo, Giuseppe Spadaro, Domenico Santoro
Guido Gembillo, Giuseppe Spadaro, Domenico Santoro, Unit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, University of Messina, Messina 98125, Italy
Co-corresponding authors: Guido Gembillo and Domenico Santoro.
Author contributions: Gembillo G, Spadaro G, and Santoro D contributed to the design, literature search, and the writing of the manuscript.
Conflict-of-interest statement: We do not have any conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guido Gembillo, MD, PhD, Assistant Professor, Unit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, University of Messina, Via Consolare Valeria, 1, Messina 98125, Italy. guidogembillo@live.it
Received: July 14, 2024
Revised: October 10, 2024
Accepted: November 19, 2024
Published online: March 25, 2025
Processing time: 190 Days and 0.1 Hours
Core Tip

Core Tip: Obstructive uropathy is a common cause of acute kidney injury. An accurate initial assessment is crucial to identify patients who may benefit from early urinary diversion and to avoid potential complications. The initial evaluation must include a physical examination, a thorough medical history, laboratory tests, and imaging studies. The treatment includes surgical and pharmacological approaches, depending on the underlying causes of the acute kidney injury, which can be multifactorial. Further research is needed to develop targeted interventions to improve patient outcomes based on multidisciplinary evaluation.