Review
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World J Nephrol. Mar 25, 2025; 14(1): 101917
Published online Mar 25, 2025. doi: 10.5527/wjn.v14.i1.101917
Gastrointestinal disease in end-stage renal disease
Ayesha Khan, Muhammad Mushtaq, Giri Movva, Aalam Sohal, Juliana Yang
Ayesha Khan, Muhammad Mushtaq, Giri Movva, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77550, United States
Aalam Sohal, Gastroenterology and Hepatology, Creighton University School of Medicine, Phoenix, AZ 85012, United States
Juliana Yang, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, TX 77555, United States
Co-first authors: Ayesha Khan and Muhammad Mushtaq.
Author contributions: Sohal A and Yang J conceptualized and designed the study, supervised the study, and made critical revisions; Khan A, Mushtaq M, and Movva G conducted the literature review, interpreted the data, created the artwork, and drafted the original manuscript. Khan A and Mushtaq M both contributed equally to the manuscript and are co-first authors.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Aalam Sohal, MBBS, MD, Academic Fellow, Gastroenterology and Hepatology, Creighton University School of Medicine, 3216 NE 45th Pl Suite 212, Phoenix, AZ 85012, United States. aalamsohal@gmail.com
Received: October 1, 2024
Revised: October 24, 2024
Accepted: January 3, 2025
Published online: March 25, 2025
Processing time: 111 Days and 16.7 Hours
Core Tip

Core Tip: Due to electrolyte imbalance, fluid imbalance, toxin buildup, uremia, medications, dietary and lifestyle restrictions, and the effects of dialysis, patients with renal failure experience gastrointestinal complications with a prevalence of 77%-79%. Common conditions include gastroesophageal reflux disease, nausea and vomiting, dysmotility within the esophagus and stomach, upper gastrointestinal bleeding, peptic ulcer bleeding, angioectasia, irritable bowel syndrome, mesenteric ischemia, angiodysplasia, diverticular disease, constipation, pancreatitis, and diseases associated with peritoneal dialysis peritonitis and peritoneal stenosis.