Systematic Reviews
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. Mar 25, 2024; 13(1): 90402
Published online Mar 25, 2024. doi: 10.5527/wjn.v13.i1.90402
Prevalence and outcomes of polycystic kidney disease in African populations: A systematic review
Modou Ndongo, Lot Motoula Nehemie, Baratou Coundoul, Abou Abdallah Malick Diouara, Sidy Mohamed Seck
Modou Ndongo, Department of Nephrology and Dialysis, Regional Hospital of Kedougou, Kedougou 26005, Senegal
Lot Motoula Nehemie, Baratou Coundoul, Sidy Mohamed Seck, Department of Nephrology and Dialysis, Military Hospital of Ouakam, Dakar 28216, Senegal
Abou Abdallah Malick Diouara, Department of Chemical Engineering and Applied Biology, Polytechnic high School of Cheikh Anta Diop University, Dakar 5085, Senegal
Sidy Mohamed Seck, Department of Nephrology, Faculty of Health Sciences, University Gaston Berger, Saint-Louis 234, Senegal
Author contributions: Seck SM and Ndongo M designed the study and performed the research; Seck SM and Ndongo M analyzed the data and wrote the manuscript; Ndongo M, Nehemie LM, Coundoul B, Diouara AAM and Seck SM edited and reviewed the manuscript; the manuscript has been read and approved by all authors.
Conflict-of-interest statement: All authors have no conflict of interest to disclose for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Modou Ndongo, MD, Doctor, Department of Nephrology and Dialysis, Regional Hospital of Kedougou, Dimboli, Route de Fongolimbi, Kedougou 26005, Senegal. ndongomodou@gmail.com
Received: December 4, 2023
Peer-review started: December 4, 2023
First decision: December 28, 2023
Revised: January 3, 2024
Accepted: March 11, 2024
Article in press: March 11, 2024
Published online: March 25, 2024
Processing time: 108 Days and 11.4 Hours
Core Tip

Core Tip: Polycystic kidney disease is the most common genetic disorder affecting the kidney. The two main forms are autosomal dominant polycystic disease and autosomal recessive polycystic disease. It can lead to numerous complications with a natural progression leading to End stage kidney disease. Though the disease is well known and described in developed countries, its characteristics are still poorly understood in Africa. Indeed, as it appear in the present review, few studies regarding this disease were performed in the continent but reveal that advanced symptoms are already present in most of patients at the time of the diagnostic and the few studies with genetic testing revealed many new mutations.