Observational Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. Dec 25, 2023; 12(5): 168-181
Published online Dec 25, 2023. doi: 10.5527/wjn.v12.i5.168
Antihypertensive prescribing patterns in non-dialysis dependent chronic kidney disease: Findings from the Salford Kidney Study
Rajkumar Chinnadurai, Henry H L Wu, Jones Abuomar, Sharmilee Rengarajan, David I New, Darren Green, Philip A Kalra
Rajkumar Chinnadurai, Sharmilee Rengarajan, David I New, Darren Green, Philip A Kalra, Donal O’Donoghue Renal Research Centre & Department of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, United Kingdom
Henry H L Wu, Department of Renal Research, Kolling Institute of Medical Research, Royal North Shore Hospital & The University of Sydney, St. Leonards (Sydney) 2065, New South Wales, Australia
Jones Abuomar, Faculty of Biology, Medicine & Health, The University of Manchester, Manchester M1 7HR, United Kingdom
Author contributions: Chinnadurai R drafted the manuscript, led the design and oversight of the study, led the data analysis, and participated in drafting and revising the manuscript; Wu HHL drafted the manuscript and participated in revising the manuscript; Abuomar J participated in the design of the study and led data collection; Rengarajan S participated in the design of the study and assisted in data collection; New D participated in revising the manuscript; Green D participated in revising the manuscript; Kalra PA supervised the design and oversight of the study and participated in revising the manuscript; All authors read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the institutional review board of the North West - Greater Manchester South Research Ethics Committee in the United Kingdom.
Informed consent statement: All study participants, or their legal guardian, provided written consent prior to study enrolment.
Conflict-of-interest statement: The authors of this manuscript declare that they have no conflicts of interest to disclose in relation to the contents of this study.
Data sharing statement: There are no additional data available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rajkumar Chinnadurai, MD, PhD, Consultant Physician-Scientist, Doctor, Senior Lecturer, Donal O’Donoghue Renal Research Centre & Department of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Stott Lane, Salford M6 8HD, United Kingdom. rajkumar.chinnadurai@nca.nhs.uk
Received: August 20, 2023
Peer-review started: August 20, 2023
First decision: September 14, 2023
Revised: September 20, 2023
Accepted: October 23, 2023
Article in press: October 23, 2023
Published online: December 25, 2023
Core Tip

Core Tip: This is an observational study that prospectively evaluated antihypertensive prescribing patterns in 3230 non-dialysis chronic kidney disease (CKD) patients over a 20-year period. Antihypertensive prescribing patterns based on CKD stage were consistent with expectations from the United Kingdom National Institute of Health and Care Excellence guideline algorithm and other international guidelines in relation to hypertension management in CKD.