Systematic Reviews
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. May 25, 2023; 12(3): 56-65
Published online May 25, 2023. doi: 10.5527/wjn.v12.i3.56
Acute renal failure with severe loin pain and patchy renal ischemia after anaerobic exercise
Hiroshi Tamura
Hiroshi Tamura, Department of Pediatrics, Kumamoto University, Kumamoto 8608556, Japan
Author contributions: Tamura H wrote the paper and collected the data.
Conflict-of-interest statement: All the author declare that they have no conflicts of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hiroshi Tamura, MD, PhD, Assistant Professor, Department of Pediatrics, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 8608556, Japan. bohm1905ht@kuh.kumamoto-u.ac.jp
Received: December 25, 2022
Peer-review started: December 25, 2022
First decision: February 8, 2023
Revised: February 22, 2023
Accepted: March 22, 2023
Article in press: March 22, 2023
Published online: May 25, 2023
Core Tip

Core Tip: Exercise is important for health maintenance and promotion. However, exercise-induced acute renal failure is a disease that athletes and doctors should be aware of. This paper makes a significant contribution to medical literature as it presents a study that investigated a not-widely-known type of exercise-induced acute renal failure known as Acute renal failure with severe Loin pain and Patchy renal ischemia after anaerobic Exercise (ALPE). Further, the study evaluated renal hypouricemia as a key risk factor of ALPE. The information in this paper can help clinicians make more accurate diagnosis, given that a significant proportion of patients with ALPE are undiagnosed. Further, this paper can increase awareness among athletes to help them prevent ALPE and reach their exercise goals.