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World J Nephrol. Nov 25, 2022; 11(6): 146-163
Published online Nov 25, 2022. doi: 10.5527/wjn.v11.i6.146
Acute kidney injury due to bilateral malignant ureteral obstruction: Is there an optimal mode of drainage?
Rabea Ahmed Gadelkareem, Ahmed Mahmoud Abdelraouf, Ahmed Mohammed El-Taher, Abdelfattah Ibrahim Ahmed
Rabea Ahmed Gadelkareem, Ahmed Mahmoud Abdelraouf, Ahmed Mohammed El-Taher, Abdelfattah Ibrahim Ahmed, Department of Urology, Assiut Urology and Nephrology Hospital, Faculty of Medicine, Assiut University, Assiut 71515, Assiut, Egypt
Author contributions: Gadelkareem RA and Abdelraouf AM designed the research, searched and collected the data, and wrote the paper; El-Taher AM and Ahmed AI contributed to design, writing and revision, and supervised the work; all authors revised and approved the paper.
Conflict-of-interest statement: The authors report having no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rabea Ahmed Gadelkareem, MD, Assistant Professor, Department of Urology, Assiut Urology and Nephrology Hospital, Faculty of Medicine, Assiut University, Elgamaa Street, Assiut 71515, Assiut, Egypt. dr.rabeagad@yahoo.com
Received: September 19, 2022
Peer-review started: September 19, 2022
First decision: October 12, 2022
Revised: October 29, 2022
Accepted: November 25, 2022
Article in press: November 25, 2022
Published online: November 25, 2022
Processing time: 73 Days and 10.2 Hours
Core Tip

Core Tip: Acute kidney injury due to malignant ureteral obstruction is a complex nephrological and urological emergency. Its management includes an initial resuscitation of the metabolic abnormalities, minimally invasive drainage of the obstructed kidneys, and correction of the underlying etiology. Several prognostic models have been proposed to clarify the best approach. However, there are controversies about the optimal mode of drainage of the kidneys, regarding the tool and laterality of drainage. Despite the practical preference of using the percutaneous nephrostomy rather than the double-J stent, the optimal mode of drainage has not been defined yet. The parameters of kidney response to drainage and the status of the underlying malignancy are important prognostic factors.