Case Report
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. Dec 17, 2018; 7(8): 155-160
Published online Dec 17, 2018. doi: 10.5527/wjn.v7.i8.155
Clear cell papillary renal cell carcinoma: A case report and review of the literature
Sung Han Kim, Whi-An Kwon, Jae Young Joung, Ho Kyung Seo, Kang Hyun Lee, Jinsoo Chung
Sung Han Kim, Whi-An Kwon, Jae Young Joung, Ho Kyung Seo, Kang Hyun Lee, Jinsoo Chung, Department of Urology, Center for Prostate Cancer, National Cancer Center, Goyang 410-769, South Korea
Author contributions: Chung J, Kwon WA and Kim SH conceived of the study, participated in its design and coordination, and helped to draft the manuscript; Chung J and Kwon WA performed the surgery; Kim SH wrote the manuscript; all authors read and approved the final manuscript.
Informed consent statement: The patient provided written informed consent for the publication of this case report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no competing interests or relevant financial relationships with either individuals or organizations.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author to: Jinsoo Chung, MD, PhD, Doctor, Department of Urology, Center for Prostate Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, Goyang 410-769, South Korea. cjs5225@ncc.re.kr
Telephone: +82-31-9201676 Fax: +82-31-9201790
Received: August 2, 2018
Peer-review started: August 3, 2018
First decision: August 21, 2018
Revised: October 29, 2018
Accepted: November 8, 2018
Article in press: November 8, 2018
Published online: December 17, 2018
Processing time: 137 Days and 18.9 Hours
Abstract

Clear cell papillary renal cell carcinoma (ccpRCC) was recently established as a distinct type of epithelial neoplasm by the International Society of Urological Pathology Vancouver Classification of Renal Neoplasia. Here, we report a case of partial nephrectomy for a ccpRCC detected during the routine follow-up of a previously treated liposarcoma in a 70-year-old male patient. The patient was referred to the urology department for a right-sided renal mass (size: 2 cm) detected during routine annual imaging follow-up for a malignant right inguinal fibrous histocytoma and liposarcoma that had been diagnosed 6 and 4 years earlier, respectively, and treated with surgery and adjuvant radiation therapy. Following partial nephrectomy, the renal mass was pathologically diagnosed as ccpRCC, and immunohistochemistry revealed carbonic anhydrase 9 (CA9) expression. No recurrences or metastases were detected on follow-up imaging for 6 months. This is the first report of partial nephrectomy for incidentally discovered CA9-positive ccpRCC.

Keywords: Clear cell; Papillary; Renal cell carcinoma; Partial nephrectomy; Carbonic anhydrase 9; Case report

Core tip: Clear cell papillary renal cell carcinoma (ccpRCC) was recently established as a distinct type of epithelial neoplasm. Here, we report a case of partial nephrectomy for a ccpRCC detected during the routine follow-up a previously treated liposarcoma in a 70-year-old male patient. The patient received partial nephrectomy, the renal mass was pathologically diagnosed as ccpRCC, and immunohistochemistry revealed carbonic anhydrase 9 (CA9) expression. No recurrences or metastases were detected on follow-up imaging for 6 mo. This is the first report of partial nephrectomy for incidentally discovered CA9-positive ccpRCC.