Observational Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. Nov 6, 2016; 5(6): 507-516
Published online Nov 6, 2016. doi: 10.5527/wjn.v5.i6.507
Prevalence of risk factors for cardiovascular and kidney disease in Brazilian healthy preschool children
Adriana Cândida da Silva, Marcelo de Sousa Tavares, Maria Goretti Moreira Guimarães Penido
Adriana Cândida da Silva, Post-graduation Program - Master in Health Sciences, Child and Adolescent Health, School of Medicine, Federal University of Minas Gerais, Santa Efigênia, Belo Horizonte, CEP 30130-100, Minas Gerais, Brazil
Marcelo de Sousa Tavares, Maria Goretti Moreira Guimarães Penido, Pediatric Nephrology Unit, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, CEP 30130-100, Minas Gerais, Brazil
Marcelo de Sousa Tavares, Maria Goretti Moreira Guimarães Penido, Pediatric Nephrology Unit, Center of Nephrology, Santa Casa de Belo Horizonte Hospital, Belo Horizonte, CEP 30150-320, Minas Gerais, Brazil
Author contributions: da Silva AC, de Sousa Tavares M and Penido MGMG contributed equally to study conception and design, to data acquisition, analysis and interpretation, on writing of article, to editing, reviewing and final approval of article.
Institutional review board statement: The Committee of Ethics in Research with Human Beings from the Municipal Health Secretariat of Belo Horizonte and Federal University of Minas Gerais approved the study.
Informed consent statement: The authors attested that all study participants, or their legal guardian, provided informed written consent prior to study enrollment and it was performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki.
Conflict-of-interest statement: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at mariagorettipenido@yahoo.com.br. Participants gave informed consent for data sharing and the presented data are anonymized. There is no risk of identification.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Maria Goretti Moreira Guimarães Penido, MD, PhD, Coordinator, Professor, Pediatric Nephrology Unit, Center of Nephrology, Santa Casa de Belo Horizonte Hospital, Rua Piaui 420, Belo Horizonte, CEP 30150-320, Minas Gerais, Brazil. mariagorettipenido@yahoo.com.br
Telephone: +55-31-999291595 Fax: +55-31-32414466
Received: June 29, 2016
Peer-review started: July 1, 2016
First decision: August 5, 2016
Revised: August 31, 2016
Accepted: September 21, 2016
Article in press: September 22, 2016
Published online: November 6, 2016
Processing time: 127 Days and 3.5 Hours
Abstract
AIM

To investigate the prevalence of nutritional parameters of risk for cardiovascular disease (CVD) and kidney diseases in healthy preschool children.

METHODS

This is an observational cross-sectional study with 60 healthy children, of both genders, aged two to six years old and 56 mothers, in Belo Horizonte, Minas Gerais, Brazil. Preschool children and their families with regular activities at public schools were invited to paticipate in the study. The following characteristics were assessed: Socio-demographic condictions, clinical health, anthropometric, biochemical, lifestyle and data on food consumption. The 56 healthy children were divided into two groups, overweight (C1) and non-overweight (C2), as well as their mothers, respectively, in overweight (M1) and non-overweight (M2). Nutritional status was defined according to results obtained through the Anthro® Software for nutritional analysis.

RESULTS

Thirty-five children were male, with mean age of 4.44 ± 1.0 years old. Eighty-nine percent of them were eutrophic, 86.7% were sedentary and they had five meals a day. Body mass index (BMI) for age and total cholesterol (TC) was higher on C1 (P = 0.0001) and high density lipoprotein cholesterol (HDL-c) was higher on C2. Mothers were 32.5 ± 7.1 years old, mostly married and employed. Eighty-six percent of them were sedentary and 62.5% were overweight with BMI = 26.38 ± 5.07 kg/m2. Eighteen percent of the overweight mothers had isolated total hypercholesterolemia (TC levels elevated) and 12.5% had low HDL-c levels. The present study showed an association between overweight and obesity during the preschool years and the correspondent mothers’ nutritional status of overweight and obesity (OR = 4.96; 95%CI: 0.558-44.17). There was a positive correlation between the food risk associated with CVD by children and mothers when their consumption was 4 times/wk (P = 0.049; r = 0.516) or daily (P = 0.000008; r = 0.892).

CONCLUSION

Analyzed children showed high rates of physical inactivity, high serum cholesterol levels and high consumption of food associated with risk for CVD and renal disease. Changes in habits should be encouraged early in kindergarten.

Keywords: Cardiovascular disease; Kidney disease; Preschool children; Food habits; Lifestyle

Core tip: This is an observational cross-sectional study with 60 healthy preschool children and 56 mothers. Children were divided in overweight and non-overweight groups, as well as their mothers. There were 35 male children, mean age 4.44 ± 1.0 years old, 89% of all children were eutrophic, 87% sedentary. Body mass index/age and total cholesterol were higher in the overweight group. Mother’s age was 32.5 ± 7.1 years old, mostly married and employed, 86% of them were sedentary, 63% overweight. There was an association between overweight and obesity during preschool years and the correspondent mothers’ nutritional status of overweight and obesity. There was a positive correlation between food risk consumption associated with cardiovascular disease by children and mothers.