Published online Jul 6, 2016. doi: 10.5527/wjn.v5.i4.328
Peer-review started: January 1, 2016
First decision: February 29, 2016
Revised: April 6, 2016
Accepted: May 10, 2016
Article in press: May 11, 2016
Published online: July 6, 2016
Processing time: 183 Days and 21.2 Hours
Nocturnal enuresis often causes considerable distress or functional impairment to patient and their parents necessitating a multidisciplinary approach from paediatrician, paediatric nephrologist, urologists and psychiatrist. Mechanisms of monosymptomatic nocturnal enuresis are mainly nocturnal polyuria, bladder overactivity and failure to awaken from sleep in response to bladder sensations. Goal oriented and etiology wise treatment includes simple behavioral intervention, conditioning alarm regimen and pharmacotherapy with desmopressin, imipramine and anticholinergic drugs. Symptoms often recurs requiring change over or combination of different modes of
treatment.
Core tip: Nocturnal enuresis often causes considerable distress to patient and their parents’ lifestyle necessitating a multidisciplinary management. Simple behavioral interventions, conditioning alarm regimen and pharmacotherapy as desmopressin, imipramine and anticholinergic drugs are the mainstay of therapy used as per underlying etiology or parents’ concern. Therapy should be structured and goal directed to reduce recurrence.