Chronic hepatitis B and occult infection in chemotherapy patients - evaluation in oncology and hemato-oncology settings: The CHOICE study

Table 1 Patient demographics of the chronic hepatitis group

Patient demographics		Number of patients	Percentage
Sex	Female	1	11.1
	Male	8	88.9
Malignancy	ALL	1	11.1
	Colon	2	22.2
	HCC	5	55.6
	Pancreas	1	11.1
USG	Coarse liver	5	55.6
	Normal	4	44.4
Past history of jaundice	No	4	44.4
	Yes	5	55.6
Positive family history	No	8	88.9
	Yes	1	11.1
Past history of surgeries	No	8	88.9
	Yes	1	11.1
History of transfusion in the past	No	8	88.9
	Yes	1	11.1
History of acute hepatitis B in the past	No	6	66.6
	Yes	3	33.3

ALL: Acute lymphoblastic leukemia; HCC: Hepatocellular carcinoma; USG: Ultrasound sonography.

Table 2 Baseline hepatitis B virus DNA levels of the chronic hepatitis with follow-up at 6 and 12 months after the introduction of prophylaxis (tenofovir or entecavir)

Patient	0 months		6th months		12th months
	HBV DNA	Liver enzymes	HBV DNA	Liver enzymes	HBV DNA	Liver enzymes
1	TND	Normal	TND	Normal	TND	Normal
2	TND	Normal	TND	Normal	TND	Normal
3	TND	Normal	TND	Normal	TND	Normal
4	TND	Normal	TND	Normal	TND	Normal
5	TND	Normal	TND	Normal	TND	Normal
6	TND	Normal	TND	Normal	TND	Normal
7	TND	Normal	TND	Normal	TND	Normal
8	HIGH	Elevated > 2X UNL	TND	Normal	TND	Normal
9	HIGH	Elevated > 2X UNL	TND	Normal	TND	Normal

HBV: Hepatitis B virus; TND: Target not detected; UNL: Upper limit of normal.

Table 3 Patient demographics of the occult hepatitis B infection group

Patient demographics		No. of patients	Percentage
Age	52 yr	1	33.3
	75 yr	1	33.3
	78 yr	1	33.3
Sex	Female	1	33.3
	Male	2	66.7
Malignancy	AML	1	33.3
	Colon	1	33.3
	NSGCT	1	33.3
USG	Normal	1	33.3
	Coarse liver	2	66.7
History of Jaundice	Yes	2	66.7
	No	1	33.3
History of blood transfusion in the past	Yes	1	33.3
	No	2	66.7
History of surgery in the past	Yes	1	33.3
	No	2	66.7
Family history	Yes	0	0.0
	No	3	100.0

AML: Acute myeloid leukemia; NSGCT: Non-seminomatous germ cell tumor; USG: Ultrasound sonography.

Table 4 Baseline hepatitis B virus DNA levels of occult hepatitis B infection group and follow-up at 6 and 12 months after the introduction of prophylaxis (tenofovir or entecavir)

Patient	0 months		6th months		12th months
	HBV DNA	Liver enzymes	HBV DNA	Liver enzymes	HBV DNA	Liver enzymes
1	TND	Normal	TND	Normal	TND	Normal
2	TND	Normal	TND	Normal	TND	Normal
3	TND	Normal	TND	Normal	TND	Normal

HBV: Hepatitis B virus; TND: Target not detected.