Basic Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Virol. Mar 25, 2025; 14(1): 96098
Published online Mar 25, 2025. doi: 10.5501/wjv.v14.i1.96098
Prevalence of transfusion transmissible infections among various donor groups: A comparative analysis
Sanjay K Thakur, Anil K Sinha, Santosh K Sharma, Aarzoo Jahan, Dinesh K Negi, Ruchika Gupta, Sompal Singh
Sanjay K Thakur, Dinesh K Negi, Regional Blood Transfusion Centre, Hindu Rao Hospital and NDMC Medical College, North Delhi 110007, Delhi, India
Sanjay K Thakur, Anil K Sinha, Department of Zoology, Veer Kunwar Singh University, Ara 802301, Bihar, India
Santosh K Sharma, Department of Pathology, Hindu Rao Hospital and NDMC Medical College, North Delhi 110007, Delhi, India
Aarzoo Jahan, Sompal Singh, Regional Blood Transfusion Centre and Pathology, Hindu Rao Hospital and NDMC Medical College, North Delhi 110007, Delhi, India
Ruchika Gupta, Department of Cytopathology, ICMR-National Institute of Cancer Prevention and Research, Noida 201301, Uttar Pradesh, India
Co-first authors: Sanjay K Thakur and Anil K Sinha.
Co-corresponding authors: Ruchika Gupta and Sompal Singh.
Author contributions: Thakur SK carried out the literature review, data collection, data analysis, and manuscript preparation; Thakur SK, Sinha AK, Gupta R and Singh S performed statistical analysis; Thakur SK, Sinha AK, Sharma SK, Negi DK, Gupta R and Singh S were responsible for the research design; all authors equally contributed to data processing, interpretation, writing, and revising the final text; all of the authors read and approved the final version of the manuscript to be published.
Institutional review board statement: The present study received approval from the Institutional Ethical Review Committee of Hindu Rao Hospital and NDMC Medical College, Delhi, No: IEC/NDMC/2021/69. All participant blood donors provided informed consent for blood donation. Data used in the study included routine blood grouping and TTI screening test results from the blood bank inventory registers. As no additional blood samples were collected from donors for the study, separate informed consent was not required.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: All study datasets are available from the corresponding author at sompalsingh@mcd.nic.in and co-corresponding author ruchika.gupta79@gov.in.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sompal Singh, MD, Regional Blood Transfusion Centre and Pathology, Hindu Rao Hospital and NDMC Medical College, Malkaganj, North Delhi 110007, Delhi, India. sompalsingh@mcd.nic.in
Received: April 26, 2024
Revised: October 16, 2024
Accepted: November 13, 2024
Published online: March 25, 2025
Processing time: 215 Days and 9.4 Hours
Core Tip

Core Tip: The study examined transfusion transmissible infection (TTI) among blood donors, assessing differences across groups: (1) In-house donors; (2) Total camp donors; (3) Institutional camp donors; and (4) Community camp donors. Findings revealed higher TTI prevalence in in-house donors (2.17%), followed by total donors (2.07%). Community camp donors and total camp donors had lower TTI rates at 1.56% and 1.27%, respectively, while institutional camp donors had the lowest rate at 0.92%. Statistical comparisons indicated significant differences in TTI prevalence between various groups.