Copyright
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Virol. Dec 25, 2024; 13(4): 98839
Published online Dec 25, 2024. doi: 10.5501/wjv.v13.i4.98839
Published online Dec 25, 2024. doi: 10.5501/wjv.v13.i4.98839
Candidemia chronicles: Retrospective analysis of candidemia epidemiology, species distribution, and antifungal susceptibility patterns in Bahrain
Nermin Kamal Saeed, Safiya Almusawi, Medical Microbiology Section, Department of Pathology, Salmaniya Medical Complex, Governmental Hospitals, Manama 12, Bahrain
Nermin Kamal Saeed, Safiya Almusawi, Department of Medical Microbiology, Royal College of Surgeons in Ireland–Bahrain, Busaiteen 15503, Bahrain
Mohammed Al-Beltagi, Department of Pediatric, Faculty of Medicine, Tanta University, Tanta 31511, Egypt
Mohammed Al-Beltagi, Department of Pediatric, University Medical Center, King Abdulla Medical City, Arabian Gulf University, Manama 26671, Bahrain
Author contributions: Saeed NK, Almusawi S, and Al-Biltagi M contributed substantially to this retrospective study's design and implementation; Saeed NK and Almusawi S were primarily responsible for data collection, ensuring accuracy and completeness; Saeed NK took the lead in drafting the initial manuscript; Almusawi S contributed significantly to the writing and organization of the content; Al-Biltagi M provided critical revisions, offering expert insights and guidance on the manuscript's scientific and clinical content; all authors reviewed and approved the final version of the manuscript.
Institutional review board statement: The Secondary Care Research Committee of Salmaniya Medical Complex, Ministry of Health, United Kingdom of Bahrain, has approved the study. However, ethical consideration was unnecessary as it was a non-interventional, retrospective study that did not expose patient data.
Informed consent statement: No informed consent was needed as the study was a retrospective analysis of the laboratory data without personnel information.
Conflict-of-interest statement: The authors declare no conflicts of interest related to this study. The research was conducted independently, without any financial or personal relationships that could have influenced the work reported in this manuscript.
Data sharing statement: The datasets generated and analyzed during this study are available from the corresponding author upon reasonable request. All data have been anonymized to ensure confidentiality and are shared in accordance with relevant ethical guidelines and institutional policies.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mohammed Al-Beltagi, MBChB, MD, PhD, Academic Editor, Chairman, Full Professor, Research Scientist, Department of Pediatric, Faculty of Medicine, Tanta University, Al-Bahr Street, The Medical Complex, Tanta 31511, Egypt.
Received: July 7, 2024
Revised: August 16, 2024
Accepted: August 26, 2024
Published online: December 25, 2024
Processing time: 102 Days and 14.6 Hours
Revised: August 16, 2024
Accepted: August 26, 2024
Published online: December 25, 2024
Processing time: 102 Days and 14.6 Hours
Core Tip
Core Tip: This study underscores the significant burden of candidemia in Bahrain, highlighting demographic trends, species distribution, antifungal susceptibility patterns, and critical risk factors over three years. The emergence of multidrug-resistant Candida species, particularly Candida auris, poses challenges to clinical management. High mortality rates underscore the critical need for early detection, prompt initiation of appropriate antifungal therapy guided by susceptibility testing, and rigorous infection control measures. Healthcare providers should prioritize antimicrobial stewardship, minimize invasive procedures when possible, and enhance surveillance efforts to mitigate the rising threat of antifungal resistance and improve patient outcomes in candidemia management.