Hanif FM, Majid Z, Ahmed S, Luck NH, Mubarak M. Hepatic manifestations of coronavirus disease 2019 infection: Clinical and laboratory perspective. World J Virol 2022; 11(6): 453-466 [PMID: 36483109 DOI: 10.5501/wjv.v11.i6.453]
Corresponding Author of This Article
Muhammed Mubarak, FCPS, Professor, Department of Pathology, Sindh Institute of Urology and Transplantation, Dewan Farooque Medical Complex, Chand Bibi Road, Karachi 74200, Sindh, Pakistan. drmubaraksiut@yahoo.com
Research Domain of This Article
Genetics & Heredity
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Virol. Nov 25, 2022; 11(6): 453-466 Published online Nov 25, 2022. doi: 10.5501/wjv.v11.i6.453
Hepatic manifestations of coronavirus disease 2019 infection: Clinical and laboratory perspective
Farina M Hanif, Zain Majid, Shoaib Ahmed, Nasir H Luck, Muhammed Mubarak
Farina M Hanif, Zain Majid, Shoaib Ahmed, Nasir H Luck, Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation, Karachi 74200, Sindh, Pakistan
Muhammed Mubarak, Department of Pathology, Sindh Institute of Urology and Transplantation, Karachi 74200, Sindh, Pakistan
Author contributions: Mubarak M and Luck NL conceived the study; Mubarak M, Majid Z and Hanif FM designed the study; Hanif FM, Ahmed S and Majid Z performed the research; All authors participated in primary and final drafting; All authors read and approved the final manuscript.
Conflict-of-interest statement: None of the authors have any conflicts of interest related to this research.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Muhammed Mubarak, FCPS, Professor, Department of Pathology, Sindh Institute of Urology and Transplantation, Dewan Farooque Medical Complex, Chand Bibi Road, Karachi 74200, Sindh, Pakistan. drmubaraksiut@yahoo.com
Received: September 12, 2022 Peer-review started: September 12, 2022 First decision: September 29, 2022 Revised: October 17, 2022 Accepted: November 7, 2022 Article in press: November 7, 2022 Published online: November 25, 2022 Processing time: 71 Days and 23.4 Hours
Core Tip
Core Tip: The novel coronavirus disease 2019 (COVID-19) has affected the entire globe with devastating consequences on the health and economy of all countries. Primarily a disease of the upper respiratory tract, it may involve multiple organs in severe cases, which are fortunately rare. The liver and gastrointestinal tract are also frequently involved in COVID-19. Involvement of the liver is multifaceted and may be asymptomatic or may lead to acute liver failure. This review article focused on various clinical presentations and laboratory abnormalities of liver function tests in patients with COVID-19. This will help in creating awareness among the general physicians, gastroenterologists, hepatologists and infectious disease consultants regarding this important complication.
