Vigliar MFR, Pomini KT, Buchaim DV, Buchaim RL. Anatomophysiological relationships and clinical considerations of taste and smell loss in patients with COVID-19. World J Virol 2022; 11(5): 362-374 [PMID: 36188742 DOI: 10.5501/wjv.v11.i5.362]
Corresponding Author of This Article
Rogerio Leone Buchaim, PhD, Associate Professor, Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla 9-75, Bauru 17012901, São Paulo, Brazil. rogerio@fob.usp.br
Research Domain of This Article
Anatomy & Morphology
Article-Type of This Article
Systematic Reviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Maria Fernanda Rossi Vigliar, Karina Torres Pomini, Rogerio Leone Buchaim, Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012901, São Paulo, Brazil
Karina Torres Pomini, Daniela Vieira Buchaim, University of Marilia, Marilia 17525902, São Paulo, Brazil
Daniela Vieira Buchaim, University Center of Adamantina, Adamantina 17800000, São Paulo, Brazil
Rogerio Leone Buchaim, Faculty of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo 05508270, São Paulo, Brazil
Author contributions: Vigliar MFR and Buchaim RL conceptualized, designed, and contributed to the outline of the review article; Pomini KT and Buchaim DV contributed to drafting, editing, and formatting of the manuscript; all authors wrote, read, and approved the final manuscript.
Conflict-of-interest statement: All authors declare no conflicts of interest for this article.
PRISMA 2009 Checklist statement: All authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rogerio Leone Buchaim, PhD, Associate Professor, Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla 9-75, Bauru 17012901, São Paulo, Brazil. rogerio@fob.usp.br
Received: April 13, 2022 Peer-review started: April 13, 2022 First decision: June 16, 2022 Revised: June 24, 2022 Accepted: August 12, 2022 Article in press: August 12, 2022 Published online: September 25, 2022 Processing time: 163 Days and 17.2 Hours
Core Tip
Core Tip: We discuss the anatomical and physiological considerations about two of the symptoms reported by patients: The loss or reduction of smell and taste. There are still few studies about the treatment, and among those addressed in this review, only two studies reported possible treatments and emphasized the scarcity of data, with the best option being treatments that do not cause harm, such as gustatory and olfactory physiotherapy. Given the scarcity of data, this review emphasizes the importance of prevention, through the correct use of personal protective equipment by health professionals and respect for local behavioral indications. It is also emphasized, through five studies, that there is a predominance of such symptoms in patients with coronavirus disease 2019, which can be a tool to control dissemination, through the early isolation of patients until the results are ready.
