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World J Virol. Jul 25, 2022; 11(4): 170-175
Published online Jul 25, 2022. doi: 10.5501/wjv.v11.i4.170
COVID-19 vaccination and myocarditis: A review of current literature
Kartik Dhaduk, Jagjit Khosla, Muzna Hussain, Vrunda Mangaroliya, Shaylika Chauhan, Kumar Ashish, Rahul Gupta, Suman Pal
Kartik Dhaduk, Muzna Hussain, Vrunda Mangaroliya, Shaylika Chauhan, Department of Internal Medicine, Geisinger Wyoming Valley Medical Center, Wilkes-Barre, PA 18702, United States
Jagjit Khosla, Department of Cardiology, University of Oklahoma, Oklahoma, OK 73019, United States
Kumar Ashish, Department of Internal Medicine, Carolina East Medical Center, North Carolina, NC 28560, United States
Rahul Gupta, Department of Medicine, Westchester Medical Center, Valhalla, NY 10595, United States
Suman Pal, Department of Internal Medicine, University of New Mexico, New Mexico, NM 87106, United States
Author contributions: Dhaduk K conceptualized the manuscript; Dhaduk K, Khosla J, Hussain M and Mangaroliya V wrote the manuscript; Chauhan S, Kumar A and Gupta R performed the literature review, concept modification; Pal S provided expert review of the manuscript; All authors have read and approved the final manuscript.
Conflict-of-interest statement: No conflict-of-interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kartik Dhaduk, MD, Staff Physician, Department of Internal Medicine, Geisinger Wyoming Valley Medical Center, 1000 E Mountain Dr, Wilkes-Barre, PA 18702, United States. kartikdhaduk@gmail.com
Received: December 24, 2021
Peer-review started: December 24, 2021
First decision: March 7, 2022
Revised: March 25, 2022
Accepted: May 22, 2022
Article in press: May 22, 2022
Published online: July 25, 2022
Processing time: 210 Days and 0.5 Hours
Core Tip

Core Tip: Coronavirus disease 2019 (COVID-19) vaccination campaign is progressing successfully, and more than 400 million vaccine doses have been administered in the United States. We support the COVID-19 vaccination drive given positive data on preventing significant morbidities from COVID-19 disease in fully vaccinated people and relatively rare occurrences of serious side effects. Many questions remain open such as: whether patients with a history of vaccine-associated myocarditis should receive the subsequent vaccines or booster doses, the long-term effect of vaccine-associated myocarditis, how to identify the high-risk individuals for such adverse reactions to selectively save vulnerable populations, etc. There is still substantial research to be done in this direction to answer unsolved questions.