Basic Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Virol. May 25, 2022; 11(3): 144-149
Published online May 25, 2022. doi: 10.5501/wjv.v11.i3.144
Omicron variant and change of electrostatic interactions between receptor binding domain of severe acute respiratory syndrome coronavirus 2 with the angiotensin-converting enzyme 2 receptor
Rujittika Mungmunpuntipantip, Viroj Wiwanitkit
Rujittika Mungmunpuntipantip, Consultant, Private Consultant, Bangkok 102002022, Thailand
Viroj Wiwanitkit, Department of Community Medicine, Dr. DY Patil University, Pune 310330, India
Author contributions: Mungmunpuntipantip R and Wiwanitkit V contributed to study conception and design, acquisition of data, and analysis and interpretation of data; Mungmunpuntipantip R drafted the article, revised it critically for important intellectual content, and approved the version of the article to be published
Conflict-of-interest statement: All authors declare that there are no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rujittika Mungmunpuntipantip, PhD, Academic Research, Additional Professor, Consultant, Private Consultant, Bangkok 102002022, Thailand. rujittika@gmail.com
Received: December 16, 2021
Peer-review started: December 16, 2021
First decision: February 21, 2022
Revised: February 21, 2022
Accepted: April 26, 2022
Article in press: April 26, 2022
Published online: May 25, 2022
Core Tip

Core Tip: Change of electrostatic interactions between receptor binding domain of severe acute respiratory syndrome coronavirus 2 with the angiotensin-converting enzyme 2 receptor can support the clinical observation that the omicron variant has increased transmissibility compared to the wild type and other variants.