Evidence Review
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Virol. Sep 25, 2021; 10(5): 217-228
Published online Sep 25, 2021. doi: 10.5501/wjv.v10.i5.217
Scientific evidence in the COVID-19 treatment: A comprehensive review
Gorane Iturricastillo, Elena Ávalos Pérez-Urría, Felipe Couñago, Pedro Landete
Gorane Iturricastillo, Elena Ávalos Pérez-Urría, Pedro Landete, Department of Pulmonology, Hospital Universitario de La Princesa, Madrid 28006, Spain
Felipe Couñago, Department of Radiation Oncology, Hospital Universitario Quirónsalud Madrid, Pozuelo de Alarcón 28223, Spain
Felipe Couñago, Department of Radiation Oncology, Hospital La Luz, Madrid 28003, Spain
Felipe Couñago, Department of Radiation Oncology Universidad Europea de Madrid, Madrid 28670, Spain
Pedro Landete, Department of Pulmonology, Universidad Autónoma de Madrid, Madrid 28049, Spain
Pedro Landete, Department of Pulmonology, Instituto Investigación Princesa, Madrid 28006, Spain
Author contributions: All authors contributed to this paper with conception and design of the manuscript, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: Authors declare no potential conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gorane Iturricastillo, MD, Doctor, Department of Pulmonology, Hospital Universitario de La Princesa, Calle Diego de Leon 62, Madrid 28006, Spain. iturricastillo.gorane@gmail.com
Received: March 17, 2021
Peer-review started: March 17, 2021
First decision: May 5, 2021
Revised: May 12, 2021
Accepted: August 9, 2021
Article in press: August 9, 2021
Published online: September 25, 2021
Processing time: 182 Days and 12 Hours
Core Tip

Core Tip: Severe acute respiratory syndrome coronavirus-2 is responsible for the unknown pneumonia that appeared in Wuhan, China, in December 2019. Lots of known drugs have been proved for coronavirus disease 2019. Corticosteroids demonstrated reduction of 28-d mortality in patients who needed oxygen and remdesivir proved to be effective reducing recovery time. Other drugs need more evaluation before establishing their effectiveness.