Nagoba BS, Dhotre SV, Gavkare AM, Mumbre SS, Dhotre PS. Convergence of COVID-19 and recurrent stroke: In-hospital mortality risks explored. World J Virol 2025; 14(1): 99904 [DOI: 10.5501/wjv.v14.i1.99904]
Corresponding Author of This Article
Basavraj S Nagoba, PhD, Professor, Department of Microbiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Vishwanathpuram, Ambajogai Road, Latur 413531, India. dr_bsnagoba@yahoo.com
Research Domain of This Article
Virology
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Virol. Mar 25, 2025; 14(1): 99904 Published online Mar 25, 2025. doi: 10.5501/wjv.v14.i1.99904
Convergence of COVID-19 and recurrent stroke: In-hospital mortality risks explored
Basavraj S Nagoba, Shree V Dhotre, Ajay M Gavkare, Sachin S Mumbre, Pradnya S Dhotre
Basavraj S Nagoba, Department of Microbiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Latur 413531, India
Shree V Dhotre, Department of Microbiology, Ashwini Rural Medical College, Solapur 413001, India
Ajay M Gavkare, Department of Physiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Latur 413531, India
Sachin S Mumbre, Department of Community Medicine, Ashwini Rural Medical College, Solapur 413001, India
Pradnya S Dhotre, Department of Biochemistry, Ashwini Rural Medical College, Solapur 413001, India
Author contributions: Nagoba BS designed the overall concept and outline of the manuscript; Dhotre SV, Gavkare AM, Mumbre SS, and Dhotre PS contributed to the discussion and design of the manuscript; Nagoba BS, Dhotre SV, and Gavkare AM contributed to the writing, and editing and literature review of the manuscript; and all authors contributed to the finalizing the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Basavraj S Nagoba, PhD, Professor, Department of Microbiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Vishwanathpuram, Ambajogai Road, Latur 413531, India. dr_bsnagoba@yahoo.com
Received: August 2, 2024 Revised: October 14, 2024 Accepted: October 24, 2024 Published online: March 25, 2025 Processing time: 117 Days and 18.8 Hours
Abstract
This editorial comments on the article by Desai et al, which investigates the impact of coronavirus disease 2019 (COVID-19) on in-hospital mortality among patients with recurrent stroke using data from the 2020 National Inpatient Sample. The findings reveal significantly higher mortality rates in COVID-19-positive patients compared to non-COVID-19 patients, particularly among middle-aged individuals, males, and ethnic minorities. This editorial explores the underlying mechanisms contributing to these outcomes and discusses the clinical implications for targeted management strategies in high-risk groups. The results emphasize the need for comprehensive approaches to mitigate the heightened risks faced by recurrent stroke patients during the COVID-19 pandemic.
Core Tip: This editorial highlighted the critical findings of heightened in-hospital mortality risk among recurrent stroke patients with coronavirus disease 2019 (COVID-19). Key findings include significantly higher mortality rates in COVID-19-positive patients, especially among middle-aged individuals, males, and ethnic minorities. The discussion explores the underlying mechanisms, such as inflammation and endothelial dysfunction, contributing to these outcomes. It also underscores the need for targeted management strategies for high-risk groups, emphasizing comprehensive approaches to mitigate risks for recurrent stroke patients during the COVID-19 pandemic. These insights aim to enhance clinical practices and improve patient outcomes in this vulnerable population.
