Zambrano LEA, Zevallos VMV, Soraya GV, Istifiani LA, Pamungkas SA, Ulhaq ZS. Transplacental transmission of dengue infection. World J Virol 2024; 13(3): 91325 [PMID: 39323447 DOI: 10.5501/wjv.v13.i3.91325]
Corresponding Author of This Article
Zulvikar Syambani Ulhaq, MD, PhD, Research Scientist, Research Center for Preclinical and Clinical Medicine, National Research and Innovation Agency Republic of Indonesia, Cibinong 16911, Indonesia. zulvikar.syambani.ulhaq@brin.go.id
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Virol. Sep 25, 2024; 13(3): 91325 Published online Sep 25, 2024. doi: 10.5501/wjv.v13.i3.91325
Transplacental transmission of dengue infection
Leonel Eslatkin Aguilar Zambrano, Victor Manuel Vasquez Zevallos, Gita Vita Soraya, Lola Ayu Istifiani, Syafrizal Aji Pamungkas, Zulvikar Syambani Ulhaq
Leonel Eslatkin Aguilar Zambrano, Victor Manuel Vasquez Zevallos, Department of Medicine, Technical University of Manabi, Manabi 130101, Ecuador
Victor Manuel Vasquez Zevallos, Department of Pediatrics, Verdi Cevallos Balda Hospital, Portoviejo 130105, Ecuador
Gita Vita Soraya, Department of Biochemistry, Hasanuddin University, Makassar 90245, Indonesia
Lola Ayu Istifiani, Department of Nutrition, Faculty of Health Sciences, Brawijaya University, Malang 65100, Indonesia
Syafrizal Aji Pamungkas, Clinic of Yayasan Dana Sosial Al Falah, Malang 65100, Indonesia
Zulvikar Syambani Ulhaq, Research Center for Preclinical and Clinical Medicine, National Research and Innovation Agency Republic of Indonesia, Cibinong 16911, Indonesia
Author contributions: Zambrano LEA, Zevallos VMV conceived the report and data collection; Zambrano LEA is the main contributor to this article; Soraya GV, Istifiani LA, Pamungkas SA performed a literature review; Ulhaq ZS conceived the report, performed a literature review, and wrote the article.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zulvikar Syambani Ulhaq, MD, PhD, Research Scientist, Research Center for Preclinical and Clinical Medicine, National Research and Innovation Agency Republic of Indonesia, Cibinong 16911, Indonesia. zulvikar.syambani.ulhaq@brin.go.id
Received: December 27, 2023 Revised: June 14, 2024 Accepted: July 4, 2024 Published online: September 25, 2024 Processing time: 246 Days and 2.2 Hours
Abstract
We specifically addressed the persistent challenge of dengue in endemic regions, highlighting the potential seriousness of dengue infection through vertical transmission. Vertical dengue transmission has been well documented, particularly in hyper-endemic regions, including Ecuador. Herein, we present a neonate diagnosed with congenital dengue and review similar cases from previously published reports. Although congenital dengue is commonly infected with severe serotypes of DENV (DENV-1 and DENV-2) infections, favorable outcomes are generally observed.
Core Tip: Dengue, caused by the dengue virus, poses a significant public health concern in tropical regions. While primarily known for its various clinical presentations, severe forms affecting pregnant women and children have been documented. Although vertical transmission of the virus from mother to fetus is uncommon, it can lead to severe complications, underscoring the need for vigilance and specialized care for both mothers and newborns.
