Liu JW, Li YY, Wang MK, Yang JS. Combined prevention and treatment measures are essential to control nosocomial infections during the COVID-19 pandemic. World J Virol 2024; 13(2): 91286 [PMID: 38984081 DOI: 10.5501/wjv.v13.i2.91286]
Corresponding Author of This Article
Ming-Ke Wang, MD, PhD, Associate Chief Physician, Department of Disease Control and Prevention, Naval Medical Center of PLA, Naval Medical University, No. 338 Huaihai West Road, Changning District, Shanghai 200052, China. wmke021@163.com
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Virol. Jun 25, 2024; 13(2): 91286 Published online Jun 25, 2024. doi: 10.5501/wjv.v13.i2.91286
Combined prevention and treatment measures are essential to control nosocomial infections during the COVID-19 pandemic
Jing-Wen Liu, Yue-Yue Li, Ming-Ke Wang, Ji-Shun Yang
Jing-Wen Liu, Yue-Yue Li, Ji-Shun Yang, Medical Care Center, Naval Medical Center of PLA, Naval Medical University, Shanghai 200052, China
Jing-Wen Liu, Yue-Yue Li, School of Pharmacy, Bengbu Medical College, Bengbu 233000, Anhui Province, China
Ming-Ke Wang, Department of Disease Control and Prevention, Naval Medical Center of PLA, Naval Medical University, Shanghai 200052, China
Co-corresponding authors: Ming-Ke Wang and Ji-Shun Yang.
Author contributions: Wang MK and Yang JS conceptualized, designed, and revised the manuscript; Liu JW drafted the manuscript; Li YY collected the literature. All authors have read and approved the final manuscript. Both Wang MK and Yang JS have conceptualized, proposed, designed, and supervised the whole process of the article, and played important and indispensable roles in the manuscript preparation and revision as the co-corresponding authors. Wang MK applied for and obtained the funds for this research project. Wang MK conceptualized, designed, revised and supervised the whole process of the project. Yang JS was instrumental, conceptualized, and revised the manuscript. This collaboration between Wang MK and Yang JS is crucial for the publication of this manuscript and other manuscripts still in preparation.
Supported byScientific Research Foundation of Shanghai Municipal Health Commission of Changning District, No. 20234Y038.
Conflict-of-interest statement: All authors have no conflict of interest related to the manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ming-Ke Wang, MD, PhD, Associate Chief Physician, Department of Disease Control and Prevention, Naval Medical Center of PLA, Naval Medical University, No. 338 Huaihai West Road, Changning District, Shanghai 200052, China. wmke021@163.com
Received: December 26, 2023 Revised: March 20, 2024 Accepted: April 10, 2024 Published online: June 25, 2024 Processing time: 180 Days and 22.2 Hours
Abstract
Severe acute respiratory syndrome coronavirus-2 is a highly contagious positive-sense, single-stranded RNA virus that has rapidly spread worldwide. As of December 17, 2023, 772838745 confirmed cases including 6988679 deaths have been reported globally. This virus primarily spreads through droplets, airborne transmission, and direct contact. Hospitals harbor a substantial number of confirmed coronavirus disease 2019 (COVID-19) patients and asymptomatic carriers, accompanied by high population density and a larger susceptible population. These factors serve as potential triggers for nosocomial infections, posing a threat during the COVID-19 pandemic. Nosocomial infections occur to varying degrees across different countries worldwide, emphasizing the urgent need for a practical approach to prevent and control the intra-hospital spread of COVID-19. This study primarily concentrated on a novel strategy combining preventive measures with treatment for combating COVID-19 nosocomial infections. It suggests preventive methods, such as vaccination, disinfection, and training of heathcare personnel to curb viral infections. Additionally, it explored therapeutic strategies targeting cellular inflammatory factors and certain new medications for COVID-19 patients. These methods hold promise in rapidly and effectively preventing and controlling nosocomial infections during the COVID-19 pandemic and provide a reliable reference for adopting preventive measures in the future pandemic.
Core Tip: During the coronavirus disease 2019 (COVID-19) pandemic, nosocomial infections severely challenged healthcare professionals worldwide. Mitigating intra-hospital diseases remains a crucial task for healthcare practitioners. This study concentrated on pivotal strategies for preventing and controlling COVID-19 infections within medical facilities. It advocated viral infection prevention through vaccination, disinfection, and the training of heathcare personnel. Simultaneously, it explored therapeutic strategies involving cellular inflammatory factors and certain new medications tailored for COVID-19 patients. These methods could prevent and control intra-hospital infections swiftly and effectively during the COVID-19 outbreak.
