Avraham D, Herman A, Shaham G, Shklyar A, Sulim E, Oulianski M. Lab results of COVID-19 patients: Omicron vs delta variants. World J Virol 2024; 13(2): 90761 [PMID: 38984078 DOI: 10.5501/wjv.v13.i2.90761]
Corresponding Author of This Article
Dana Avraham, MD, Doctor, Orthopedic Department, Kaplan Medical Center, Pasternak 1, Rehovot 7661041, Israel. danaav7111@gmail.com
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Virol. Jun 25, 2024; 13(2): 90761 Published online Jun 25, 2024. doi: 10.5501/wjv.v13.i2.90761
Lab results of COVID-19 patients: Omicron vs delta variants
Dana Avraham, Amir Herman, Gal Shaham, Arkady Shklyar, Elina Sulim, Maria Oulianski
Dana Avraham, Amir Herman, Maria Oulianski, Orthopedic Department, Kaplan Medical Center, Rehovot 7661041, Israel
Gal Shaham, Department of Medicine, Lithuanian University of Health Sciences, Kaunas 44307, Lithuania
Arkady Shklyar, Elina Sulim, Emergency Department, Kaplan Medical Center, Rehovot 7661041, Israel
Author contributions: Avraham D and Oulianski M designed the research; Herman A and Shaham G performed the research; Shklyar A contributed new reagents/analytic tools; Oulianski M and Sulim A analyzed the data; Avraham D and Oulianski M wrote the paper.
Institutional review board statement: The study was reviewed and approved by the "Kaplan Medical Center" Helsinki Committee Institutional Review Board [(Approval No. 0018-22-KMC]).
Informed consent statement: According to the Helsinki Committee decision, our study does not require inform consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The authors commit to making the data and materials underlying the findings of this medical article available upon reasonable request. Requests for data should be directed to [Dr. Dana Avraham at Danaav7111@gmail.com. The authors aim to facilitate transparency and reproducibility in scientific research and encourage collaboration within the scientific community. Access to the data will be provided in compliance with ethical standards and institutional regulations.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dana Avraham, MD, Doctor, Orthopedic Department, Kaplan Medical Center, Pasternak 1, Rehovot 7661041, Israel. danaav7111@gmail.com
Received: December 12, 2023 Revised: January 26, 2024 Accepted: March 6, 2024 Published online: June 25, 2024 Processing time: 194 Days and 13.3 Hours
Abstract
BACKGROUND
The coronavirus disease 2019 (COVID-19) virus has been a world-known pandemic since February 2020. Multiple variances had been established; the most common variants in Israel were omicron and delta.
AIM
To analyze and compare laboratory values in the "omicron" and "delta" variants of the coronavirus by conducting follow-up examinations and laboratory audits on COVID-19 patients admitted to our institution.
METHODS
A retrospective study, two groups, 50 patients in each group. Patients examined positive for COVID-19 were divided into groups according to the common variant at the given time. We reviewed demographic data and laboratory results such as complete blood count and full chemistry, including electrolytes and coagulation parameters.
RESULTS
The mean age was 52%, 66.53 ± 21.7 were female. No significance was found comparing laboratory results in the following disciplines: Blood count, hemoglobin, and lymphocytes (P = 0.41, P = 0.87, P = 0.97). Omicron and delta variants have higher neutrophil counts, though they are not significantly different (P = 0.38). Coagulation tests: Activated paritial thromoplastin test and international normalized ratio (P = 0.72, P = 0.68). We found no significance of abnormality for all electrolytes.
CONCLUSION
The study compares laboratory results of blood tests between two variants of the COVID-19 virus – omicron and delta. We found no significance between the variants. Our results show the need for further research with larger data as well as the need to compare all COVID-19 variants.
Core Tip: We reviewed lab results of patient positive for coronavirus disease 2019 (COVID-19) during the periods of omicron and delta variants in Israel. retrospective study of patient 18-99 YO excluding pregnant and oncologic patients. The neutrophil index increased above the normal level. There was no difference between the variants in the other count parameters (hemoglobin and white blood cell count) and coagulation functions (activated paritial thromoplastin test, international normalized ratio) and electrolytes (sodium, chloride, phosphorus, and albumin) had no significant variances or deviations from the acceptable norma. hypokalemia was measured in 62% of all COVID-19 patients.
