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World J Virol. Jun 25, 2023; 12(3): 204-208
Published online Jun 25, 2023. doi: 10.5501/wjv.v12.i3.204
Etiopathogenic theories about long COVID
Luis Del Carpio-Orantes
Luis Del Carpio-Orantes, Department of Internal Medicine, Virology, Research, Study Group for the Diagnosis and Treatment of COVID-19 in Veracruz, Veracruz 91900, Veracruz, Mexico
Author contributions: Del Carpio-Orantes L contributed to conceptualized the idea of the review, searched for information for the review, wrote the document, provided a summary of the information on the diagnosis and treatment chart.
Conflict-of-interest statement: The author declares no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Luis Del Carpio-Orantes, MD, Research Scientist, Department of Internal Medicine, Virology, Research, Study Group for the Diagnosis and Treatment of COVID-19 in Veracruz, 12 de Octubre 603, Veracruz 91900, Veracruz, Mexico. neurona23@hotmail.com
Received: January 15, 2023
Peer-review started: January 15, 2023
First decision: March 1, 2023
Revised: April 8, 2023
Accepted: May 12, 2023
Article in press: May 12, 2023
Published online: June 25, 2023
Processing time: 156 Days and 10.6 Hours
Abstract

The main etiopathogenic theories of long coronavirus disease (COVID) are listed and a conjunction of them is carried out with the objective of deciphering the pathophysiology of the entity, finally the main lines of treatment existing in real life are discussed (Paxlovid, use of antibiotics in dysbiosis, triple anticoagulant therapy, temelimab).

Keywords: Long COVID, Viral persistence, Amyloid microthrombosis, Dysbiosis, Weakened immune system, Paxlovid, Triple therapy

Core Tip: List the main etiopathogenic theories of long coronavirus disease (COVID) and evaluate their interrelation as pathophysiological agents of long COVID syndrome.