Predictive value of tacrolimus concentration/dose ratio in first post-transplant week for CYP3A5-polymorphism in kidney-transplant recipients

Figure 1 Comparison of C0 concentrations, concentration-to-dose ratio between CYP3A5 metabolizers in renal transplant recipients. A: Comparisons of C0 concentrations between CYP3A5 fast metabolizers and slow metabolizers in renal transplant recipients; B: Comparisons of concentration-to-dose ratio between CYP3A5 fast metabolizers and slow metabolizers in renal transplant recipients. ^aP < 0.001. C0/D: Concentration-to-dose.

Figure 2 Receiver operating characteristic curve analysis of the concentration-to-dose ratio at time points for the prediction of CYP3A5 polymorphism. ROC: Receiver operating characteristic; C0/D: Concentration-to-dose.