Copyright
©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Jun 24, 2016; 6(2): 306-313
Published online Jun 24, 2016. doi: 10.5500/wjt.v6.i2.306
Published online Jun 24, 2016. doi: 10.5500/wjt.v6.i2.306
Loco-regional therapies for patients with hepatocellular carcinoma awaiting liver transplantation: Selecting an optimal therapy
Thomas J Byrne, Jorge Rakela, Division of Gastroenterology and Hepatology, Mayo Clinic in Arizona, Phoenix, AZ 85054, United States
Author contributions: Byrne TJ and Rakela J contributed equally to the work; Byrne TJ and Rakela J conceptualized the review; Byrne TJ drafted the original manuscript; both authors reviewed and approved the final manuscript as submitted.
Conflict-of-interest statement: The authors declare no conflicts of interest regarding this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Thomas J Byrne, MD, Consultant, Assistant Professor of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic in Arizona, 5777 East Mayo Boulevard, Phoenix, AZ 85054, United States. byrne.thomas1@mayo.edu
Telephone: +1-480-3420238 Fax: +1-480-3242324
Received: October 19, 2015
Peer-review started: October 21, 2015
First decision: December 28, 2015
Revised: February 2, 2016
Accepted: March 22, 2016
Article in press: March 23, 2016
Published online: June 24, 2016
Peer-review started: October 21, 2015
First decision: December 28, 2015
Revised: February 2, 2016
Accepted: March 22, 2016
Article in press: March 23, 2016
Published online: June 24, 2016
Core Tip
Core tip: Hepatocellular carcinoma has increased in incidence in recent decades. Liver transplantation is an excellent therapy for carefully selected patients. Due to the risk of tumor progression while awaiting liver transplantation, loco-regional therapy is frequently used in this setting. An expanding array of treatment options exist and are herein characterized, including descriptions of which modality may be ideal in various settings.