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World J Transplant. Mar 24, 2016; 6(1): 199-205
Published online Mar 24, 2016. doi: 10.5500/wjt.v6.i1.199
Hematopoietic stem cell transplantation for auto immune rheumatic diseases
Subramanian Ramaswamy, Sandeep Jain, Vinod Ravindran
Subramanian Ramaswamy, Department of Rheumatology and Immunology, JSS Medical College, Mysuru 570015, Karnataka, India
Sandeep Jain, Department of Medical Oncology, Mayo Clinic Health System, Albert Lea, MN 56007, United States
Vinod Ravindran, Centre for Rheumatology, Near Chevarambalam Junction, Kozhikode 673009, Kerala, India
Author contributions: Jain S and Ravindran V conceptualized this review and defined the objectives; Ramaswamy S did the literature search, identified studies and wrote the first draft; all three authors critically revised the manuscript and approved the final version.
Conflict-of-interest statement: All authors have none to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Sandeep Jain, MBBS, MRCP (UK), Senior Associate Consultant, Department of Medical Oncology, Mayo Clinic Health System, 404 W Fountain St., Albert Lea, MN 56007, United States. drsandeepjain@gmail.com
Telephone: +1-507-3792050 Fax: +1-507-3792059
Received: July 9, 2015
Peer-review started: July 14, 2015
First decision: September 22, 2015
Revised: November 4, 2015
Accepted: December 17, 2015
Article in press: December 18, 2015
Published online: March 24, 2016
Processing time: 253 Days and 3.1 Hours
Core Tip

Core tip: Hematopoietic stem cell transplantation for the management of autoimmune rheumatic diseases has come a long way. It is being recognized as a viable option in severe autoimmune diseases, in particular for systemic sclerosis.