Kontogiannis CD, Malliaras K, Kapelios CJ, Mason JW, Nanas JN. Continuous internal counterpulsation as a bridge to recovery in acute and chronic heart failure. World J Transplant 2016; 6(1): 115-124 [PMID: 27011909 DOI: 10.5500/wjt.v6.i1.115]
Corresponding Author of This Article
John N Nanas, MD, PhD, 3rd Department of Cardiology, University of Athens School of Medicine, 67 Mikras Asias Street, 11527 Athens, Greece. jnanas@ath.forthnet.gr
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Transplant. Mar 24, 2016; 6(1): 115-124 Published online Mar 24, 2016. doi: 10.5500/wjt.v6.i1.115
Continuous internal counterpulsation as a bridge to recovery in acute and chronic heart failure
Christos D Kontogiannis, Konstantinos Malliaras, Chris J Kapelios, Jay W Mason, John N Nanas
Christos D Kontogiannis, Konstantinos Malliaras, Chris J Kapelios, John N Nanas, 3rd Department of Cardiology, University of Athens School of Medicine, 11527 Athens, Greece
Jay W Mason, Cardiology Division, University of Utah, Salt Lake City, UT 84132, United States
Author contributions: Kontogiannis CD, Malliaras K and Nanas JN wrote the manuscript; Kapelios CJ and Mason JW reviewed the manuscript and provided critical input; all authors approved the final draft.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: John N Nanas, MD, PhD, 3rd Department of Cardiology, University of Athens School of Medicine, 67 Mikras Asias Street, 11527 Athens, Greece. jnanas@ath.forthnet.gr
Telephone: +30-210-8236877 Fax: +30-210-7789901
Received: September 10, 2015 Peer-review started: September 10, 2015 First decision: October 16, 2015 Revised: December 27, 2015 Accepted: January 21, 2016 Article in press: January 22, 2016 Published online: March 24, 2016 Processing time: 190 Days and 11.9 Hours
Core Tip
Core tip: The counterpulsation technique induces beneficial effects on systemic hemodynamics and left ventricular mechanoenergetics. In this manner, it may facilitate myocardial recovery in acute and chronic heart failure (HF). The intra-aortic balloon pump (IABP) remains the main representative of the counterpulsation technique. Although recent data have questioned the effectiveness of short-term hemodynamic support with IABP in cardiogenic shock complicating myocardial infarction, the issue remains open to further investigation. Preliminary data suggest that long-term IABP support in patients with end-stage HF is safe and may mediate recovery of left- or/and right-sided cardiac function. Novel, fully implantable counterpulsation devices, which enable long-term counterpulsation, are described in this manuscript.
