Brief Article
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World J Transplant. Dec 24, 2013; 3(4): 127-133
Published online Dec 24, 2013. doi: 10.5500/wjt.v3.i4.127
Isolated small bowel transplantation outcomes and the impact of immunosuppressants: Experience of a single transplant center
Ibtesam A Hilmi, Raymond M Planinsic, Ramona Nicolau-Raducu, Daniela Damian, Ali Al-Khafaji, Tetsuro Sakai, Kareem Abu-Elmagd
Ibtesam A Hilmi, Raymond M Planinsic, Daniela Damian, Tetsuro Sakai, Department of Anesthesiology, University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh, PA 15213, United States
Ramona Nicolau-Raducu, Department of Anesthesiology, Ochsner Health System, New Orleans, LA 70121, United States
Ali Al-Khafaji, Transplant Intensive Care Unit, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, United States
Kareem Abu-Elmagd, Center for Gut Rehabilitation and Transplantation, Cleveland, OH 44195, United States
Author contributions: Hilmi IA wrote the study protocol and study design, collected the data, and wrote the manuscript; Planinsic RM reviewed the scientific material and edited the manuscript; Nicolau-Raducu R and Damian D collected the data and performed the statistical analysis; Al-Khafaji A reviewed the scientific material and study design and participated in data collection and analysis; Sakai T and Abu-Elmagd K provided the data, served as scientific advisors, and participated in the manuscript writing.
Supported by The Department of Anesthesiology at the University of Pittsburgh Medical Center
Correspondence to: Ibtesam A Hilmi, MBCHB, FRCA, Associate Professor of Anesthesiology, Department of Anesthesiology, University of Pittsburgh Medical Center, Presbyterian Hospital, C-wing Suite 200,200 Lothrop St., Pittsburgh, PA 15213, United States. hilmiia@anes.upmc.edu
Telephone: +1-412-6473262 Fax: +1-412-6476290
Received: March 15, 2013
Revised: June 4, 2013
Accepted: July 18, 2013
Published online: December 24, 2013
Processing time: 291 Days and 16.3 Hours
Core Tip

Core tip: Small bowel transplant (SBTx) is the treatment of choice for patients with intestinal failure. However, patient and graft survival can be affected by multiple factors, such as the choice of immunosuppressant and immune induction agent. Studying the effects of these agents may help care providers customize the immunosuppressant protocol to the individual patient. In this study, we reviewed in great detail how different immune induction agents can impact the intraoperative and postoperative course, as well as the short term outcome of these patients. Such information can be of great value to physicians who treat SBTx recipients.