Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Sep 18, 2025; 15(3): 102798
Published online Sep 18, 2025. doi: 10.5500/wjt.v15.i3.102798
Introducing hyperspectral imaging as a novel tool for assessing donor liver quality during machine perfusion: A case report
Mohamed El-Mahrouk, Cord Langner, Robert Sucher, Daniela Kniepeiss
Mohamed El-Mahrouk, Robert Sucher, Daniela Kniepeiss, Division of General, Visceral and Transplantation Surgery, Department of Surgery, Medical University of Graz, Graz 8036, Steiermark, Austria
Cord Langner, Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz 8036, Steiermark, Austria
Author contributions: El-Mahrouk M wrote the manuscript and analyzed case; Langner C contributed to histological image and interpretation; Sucher R contributed to hyperspectral imaging interpretation and improving manuscript; Kniepeiss D was the supervisor.
Informed consent statement: This case involves a liver from a deceased donor, so no signed consent for treatment form(s) or document(s) is required.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mohamed El-Mahrouk, Division of General, Visceral and Transplantation Surgery, Department of Surgery, Medical University of Graz, Auenbruggerplatz 29, Graz 8036, Steiermark, Austria. mohamed.el-mahrouk@medunigraz.at
Received: November 7, 2024
Revised: February 2, 2025
Accepted: February 25, 2025
Published online: September 18, 2025
Processing time: 167 Days and 10.7 Hours
Core Tip

Core Tip: This case report highlights the potential of hyperspectral imaging (HSI) as a valuable tool for assessing machine-perfused donor liver viability. By integrating HSI with laboratory and histological data, this method provides non-invasive insights into tissue oxygenation and morphology, aiding in organ quality evaluation and supporting decisions on transplantation suitability. This case underscores HSI’s potential as a valuable tool in pre-transplant liver evaluation.