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World J Transplant. Sep 18, 2024; 14(3): 96637
Published online Sep 18, 2024. doi: 10.5500/wjt.v14.i3.96637
Challenges related to clinical decision-making in hepatocellular carcinoma recurrence post-liver transplantation: Is there a hope?
Nourhan Badwei
Nourhan Badwei, Department of Tropical Medicine, Gastroenterology and Hepatology, Hepatoma Group, Ain Shams University, Cairo 11517, Egypt
Author contributions: Badwei N contributed to collecting, designing the research data, and writing the manuscript with critical final revision and editing.
Conflict-of-interest statement: The author declares no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nourhan Badwei, MD, PhD, Lecturer, Department of Tropical Medicine, Gastroenterology and Hepatology, Hepatoma Group, Ain Shams University, Abbasiya Street, Cairo 11517, Egypt. nourhanbadwei1990@gmail.com
Received: May 11, 2024
Revised: June 8, 2024
Accepted: June 24, 2024
Published online: September 18, 2024
Processing time: 80 Days and 16.8 Hours
Core Tip

Core Tip: In this review, challenges and debates related to the management of hepatocellular carcinoma recurrence after liver transplantation (LT) were carefully handled, discussing the risk factors, pre/post-LT prediction models of tumour recurrence, and different therapeutic approaches either curative or ablative in the settings of post-LT immunosuppression.