Retrospective Cohort Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Sep 18, 2024; 14(3): 93561
Published online Sep 18, 2024. doi: 10.5500/wjt.v14.i3.93561
Recipient functional status impacts on short and long-term intestinal transplant outcomes in United States adults
Sarpong Boateng, Prince Ameyaw, Solomon Gyabaah, Yaw Adjepong, Basile Njei
Sarpong Boateng, Prince Ameyaw, Department of Medicine, Yale New Haven Health, Bridgeport Hospital, Bridgeport, CT 06610, United States
Sarpong Boateng, Department of Epidemiology and Biostatistics, University of North Texas, Fort Worth, TX 76107, United States
Solomon Gyabaah, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi KS 1934, Ghana
Yaw Adjepong, Yale University School of Medicine, New Haven, CT 06520, United States
Basile Njei, Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT 06520, United States
Author contributions: Boateng S designed the research study; Boateng S, Adjepong Y and Njei B analyzed the data; Boateng S, Ameyaw P, Gyabaah S, Adjepong Y and Njei B wrote the manuscript. All authors have read and approved the final manuscript.
Institutional review board statement: Study contained deidentified patient information and was thus deemed IRB exempt by the Yale New Haven Health Institutional review board.
Informed consent statement: Consent was not obtained but the presented data are anonymized and risk of identification is low.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest, financial or otherwise, to disclose in relation to this study. There are no funding sources for the manuscript.
Data sharing statement: All datasets were extracted and analyzed from the UNOS Program. The data is publicly available online at https://unos.org/
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sarpong Boateng, MD, Doctor, Department of Medicine, Yale New Haven Health, Bridgeport Hospital, 267 Grant Street, Bridgeport, CT 06610, United States. sarpong1500@gmail.com
Received: February 29, 2024
Revised: May 27, 2024
Accepted: June 13, 2024
Published online: September 18, 2024
Processing time: 152 Days and 14.5 Hours
Core Tip

Core Tip: Pre- and post-transplant assessment of recipient functional status using the Karnofsky Performance Status scale is crucial for predicting short- and long-term outcomes in intestinal transplantation. Severe impairment significantly increases the risk of mortality at one- and five-years post-transplant, emphasizing the importance of comprehensive pre-transplant evaluation and potential interventions to optimize functional status in recipients undergoing intestinal transplantation in the United States.