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Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Dec 18, 2023; 13(6): 309-320
Published online Dec 18, 2023. doi: 10.5500/wjt.v13.i6.309
BK viral infection: A review of management and treatment
June Hayrelle Gorriceta, Amy Lopez Otbo, Genta Uehara, Maria Aurora Posadas Salas
June Hayrelle Gorriceta, Department of Medicine, St Francis Hospital-Bartlett, Bartlett, TN 38133, United States
Amy Lopez Otbo, Department of Medicine, St. Luke’s Medical Center, Quezon 1112, Philippines
Genta Uehara, Maria Aurora Posadas Salas, Department of Medicine, Division of Nephrology, Medical University of South Carolina, Charleston, SC 29425, United States
Author contributions: Gorriceta JH contributed to the manuscript, revised the manuscript; Lopez Otbo A contributed to the manuscript, revised the manuscript; Uehara G contributed to the manuscript, revised the manuscript; Posadas Salas MA conceptualized the manuscript, contributed to the manuscript, revised the manuscript.
Conflict-of-interest statement: The authors have no conflict of interest to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Maria Aurora Posadas Salas, MD, Professor, Department of Medicine, Division of Nephrology, Medical University of South Carolina, No. 96 Jonathan Lucas Street, Charleston, SC 29425, United States. posadas@musc.edu
Received: September 8, 2023
Peer-review started: September 10, 2023
First decision: September 29, 2023
Revised: November 15, 2023
Accepted: November 30, 2023
Article in press: November 30, 2023
Published online: December 18, 2023
Core Tip

Core Tip: BK viral infection is a significant post-transplant infection, which can result in kidney dysfunction if left unaddressed. The mainstay approach to BK infection is reduction of immunosuppression. Data on specific therapies have remained equivocal. In this article, we will review recent evidence available in literature on treatment approaches to BK viral infection.