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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Dec 28, 2020; 10(12): 392-403
Published online Dec 28, 2020. doi: 10.5500/wjt.v10.i12.392
Published online Dec 28, 2020. doi: 10.5500/wjt.v10.i12.392
Exocrine drainage in pancreas transplantation: Complications and management
Joana Ferrer-Fàbrega, HepatoBiliaryPancreatic Surgery and Liver and Pancreas Transplantation Department, ICMDM, Hospital Clinic Barcelona, University of Barcelona, Barcelona Clinic Liver Cancer Group, August Pi i Sunyer Biomedical Research Institute, Barcelona 08036, Barcelona, Spain
Laureano Fernández-Cruz, Department of Surgery, ICMDM, Hospital Clinic Barcelona, Barcelona 08036, Barcelona, Spain
Author contributions: Ferrer-Fàbrega J and Fernández-Cruz L designed the study, performed the research and analyzed the data; Ferrer-Fàbrega J wrote the manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Joana Ferrer-Fàbrega, MD, PhD, Associate Professor, Surgeon, HepatoBiliaryPancreatic Surgery and Liver and Pancreas Transplantation Department, ICMDM, Hospital Clinic Barcelona, University of Barcelona, Barcelona Clinic Liver Cancer Group, August Pi i Sunyer Biomedical Research Institute, Carrer de Villarroel, 170, Barcelona 08036, Barcelona, Spain. 2008jff@gmail.com
Received: June 22, 2020
Peer-review started: June 22, 2020
First decision: October 6, 2020
Revised: November 23, 2020
Accepted: December 8, 2020
Article in press: December 8, 2020
Published online: December 28, 2020
Peer-review started: June 22, 2020
First decision: October 6, 2020
Revised: November 23, 2020
Accepted: December 8, 2020
Article in press: December 8, 2020
Published online: December 28, 2020
Core Tip
Core Tip: A review of recent post-transplant complications regarding bladder drainage (urologic complications), enteric drainage (leak), surgical infections and abdominal compartment syndrome. Although safe and effective, bladder drainage brings metabolic and urologic complications; therefore, physiologic enteric drainage is preferred. Nevertheless, intra-abdominal infections and laparotomies arising from complications may result in significant graft loss. New modifications of established techniques are being developed, such as gastric or duodenal exocrine drainage. Donor-related factors, preservation injury, and surgical techniques should be managed to minimize adverse post-transplant events.