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World J Transplant. Jun 28, 2018; 8(3): 68-74
Published online Jun 28, 2018. doi: 10.5500/wjt.v8.i3.68
Vaccination practices in End Stage Renal Failure and Renal Transplantation; Review of current guidelines and recommendations
Nalaka Gunawansa, Roshni Rathore, Ajay Sharma, Ahmed Halawa
Nalaka Gunawansa, National Institute of Nephrology Dialysis and Transplantation, Sri Lanka and Faculty of Health and Science, Institute of Learning and Teaching, University of Liverpool, Liverpool 111, United Kingdom
Roshni Rathore, Department of Renal, University Hospitals of Coventry and Warwickshire and Faculty of Health and Science, Institute of Learning and Teaching, University of Liverpool, Liverpool 111, United Kingdom
Ajay Sharma, Ahmed Halawa, Faculty of Health and Science, Institute of Learning and Teaching, University of Liverpool and Royal Liverpool University Hospital, Liverpool 111, United Kingdom
Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Nalaka Gunawansa, MBBS, MD, MS, MCh, FCSSL, Vascular and Transplant Surgeon, National Institute of Nephrology Dialysis and Transplantation, Sri Lanka and Faculty of Health and Science, Institute of Learning and Teaching, University of Liverpool, Liverpool 111, United Kingdom. vascular@drnalakagunawansa.com
Telephone: +44-94-773737644
Received: November 24, 2017
Peer-review started: November 24, 2017
First decision: January 6, 2018
Revised: February 2, 2018
Accepted: March 13, 2018
Article in press: March 13, 2018
Published online: June 28, 2018
Processing time: 214 Days and 19.7 Hours
Abstract

Due to the increased burden of infectious complications following solid organ transplantation, vaccination against common pathogens is a hugely important area of discussion and application in clinical practice. Reduction in infectious complications will help to reduce morbidity and mortality post-transplantation. Immunisation history is invaluable in the work-up of potential recipients. Knowledge of the available vaccines and their use in transplant recipients, donors and healthcare providers is vital in the delivery of quality care to transplant recipients. This article will serve as an aide-memoire to transplant physicians and health care professionals involved in managing transplant recipients as it provides an overview of different types of vaccines, timing of vaccination, vaccines contraindicated post solid organ transplantation and travel vaccines.

Keywords: Immunization, Travel vaccines, Infection, Immunosuppression, Inactivated vaccines, Vaccination post-transplant

Core tip: Patients in end-stage renal failure and those after renal transplantation have a higher risk of opportunistic infections with catastrophic complications and poor response to standard vaccines. Special individualized consideration is needed to immunize these patients within the existing vaccination protocols.