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World J Rheumatol. Nov 12, 2013; 3(3): 12-15
Published online Nov 12, 2013. doi: 10.5499/wjr.v3.i3.12
Published online Nov 12, 2013. doi: 10.5499/wjr.v3.i3.12
X chromosome inactivation and autoimmune diseases
Ghazi Chabchoub, Laboratoire de Génétique Moléculaire Humaine, Faculté de Médecine de Sfax, 3021 Sfax, Tunisie
Author contributions: Chabchoub G solely contributed to this paper.
Correspondence to: Ghazi Chabchoub, MD, PhD, Laboratoire de Génétique Moléculaire Humaine, Faculté de Médecine de Sfax, Caisse National d’assurance Maladie, Rue Mongi Slim Sakiet Ezzit, 3021 Sfax, Tunisie. ghazi.chabchoub@laposte.net
Telephone: +216-98-291120 Fax: +216-74-856010
Received: May 29, 2013
Revised: August 21, 2013
Accepted: September 4, 2013
Published online: November 12, 2013
Processing time: 173 Days and 21.3 Hours
Revised: August 21, 2013
Accepted: September 4, 2013
Published online: November 12, 2013
Processing time: 173 Days and 21.3 Hours
Core Tip
Core tip: The causes and mechanisms for sex imbalance are based on several hypotheses. X chromosome inactivation is an important hypothesis to explain the female preponderance.