Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Rheumatol. Jan 7, 2025; 12(1): 101278
Published online Jan 7, 2025. doi: 10.5499/wjr.v12.i1.101278
Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome as a cause of pneumothorax: A case report
Zi-Xiang Zheng, Meng-Jiao Gu, Tian-Lun Kang, Yu-Ru Zhang, Yu-Nuo Wang, Chen Li, Yuan-Hao Wu
Zi-Xiang Zheng, Meng-Jiao Gu, Yu-Ru Zhang, Yu-Nuo Wang, Yuan-Hao Wu, Department of Rheumatology and Immunology, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Zi-Xiang Zheng, Meng-Jiao Gu, Yu-Nuo Wang, Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Zi-Xiang Zheng, Meng-Jiao Gu, Yu-Ru Zhang, Yu-Nuo Wang, Yuan-Hao Wu, Department of Rheumatology and Immunology, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China
Tian-Lun Kang, Department of Rheumatism, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100000, China
Chen Li, Department of Chinese Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Co-first authors: Zi-Xiang Zheng and Meng-Jiao Gu.
Co-corresponding authors: Chen Li and Yuan-Hao Wu.
Author contributions: Zheng ZX and Gu MJ collected the case content and wrote the manuscript; Kang TL and Zhang YR provided guidance on manuscript writing; Wang YN was responsible for finding relevant materials; Li C and Wu YH jointly proposed the overall direction of the topic. All authors have read and approved the final manuscript.
Supported by The National Natural Science Foundation of China, No. 82074246.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chen Li, Doctor, MD, Chief Doctor, Staff Physician, Department of Chinese Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 9 Dongdansanlu, Dongcheng District, Beijing 100730, China. casio1981@163.com
Received: September 9, 2024
Revised: December 4, 2024
Accepted: December 30, 2024
Published online: January 7, 2025
Processing time: 118 Days and 14.6 Hours
Core Tip

Core Tip: This case report introduces a novel association between synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome and pneumothorax. The 44-year-old patient’s diagnosis and treatment underscore the importance of recognizing this rare but serious condition, broadening our understanding of SAPHO syndrome’s clinical manifestations.