Effect of infarct location and volume on cognitive dysfunction in elderly patients with acute insular cerebral infarction

Table 1 Comparison of general data between two groups of patients

Variable	Cognitive impairment group, n = 58	Non-cognitive impairment group, n = 40	t/χ2	P value
Sex			0.345	0.557
Male	41	28
Female	17	12
Age in years	65.84 ± 8.13	63.19 ± 7.57	1.673	0.692
Smoking history			0.082	0.783
Yes	23	16
No	35	24
Drinking history			0.367	0.674
Yes	31	27
No	27	23
Complicated with hypertension			0.815	0.363
Yes	27	19
No	31	21
Complicated with diabetes			0.459	0.582
Yes	15	9
No	43	31
Years of education	5.78 ± 4.72	6.12 ± 4.95	3.683	0.062
Handedness			0.175	0.684
Right-handed	52	36
Left-handed	6	4

Table 2 Comparison of different infarct sites between the two groups

Variable	Cognitive impairment group, n = 58	Non-cognitive impairment group, n = 40	χ2	P value
Basal ganglia	41 (70.69)	14 (35.23)	12.245	< 0.001
Cortical layer	5 (9.39)	5 (11.95)	0.081	0.776
Brain stem	4 (6.56)	4 (9.00)	0.31	0.86
Cerebellum	5 (9.00)	4 (11.00)	0.015	0.902
Thalamus	23 (39.66)	7 (17.13)	5.471	0.019
Mix	7 (12.83)	6 (15.69)	0.177	0.674

Data are n (%).

Table 3 Comparison of infarct volume at different infarct sites between the two groups

Variable	Cognitive impairment group, n = 58	Non-cognitive impairment group, n = 40	t value	P value
Basal ganglia	48.55 ± 1.32	24.76 ± 1.01	96.161	< 0.001
Cortical layer	194.26 ± 3.75	110.02 ± 2.64	122.577	< 0.001
Brain stem	112.23 ± 3.64	72.65 ± 2.03	62.346	< 0.001
Cerebellum	81.05 ± 2.02	31.86 ± 1.04	141.47	< 0.001
Thalamus	15.87 ± 1.02	7.32 ± 0.57	48.045	< 0.001
Mixed lesions	289.84 ± 8.13	163.19 ± 6.53	81.932	< 0.001

Data are presented in mm³.