Impact of comorbid subthreshold depressive symptoms on cancer-related fatigue and complications in adults with leukemia

doi:10.5498/wjp.v14.i7.1009

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 14, Issue 7

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (1864)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-2) series, Tables (1-4) series.

Item

Count

PDF

HTML

864

Figures (1-2)

135

Tables (1-4)

140

Sum=1177

Featured Article

The chart showing Browse series, Download series.

Item

Count

Browse

143

Download

314

Sum=457

Publishing Process of This Article

Item

Count

Browse

Download

160

Sum=191

Jul 19, 2024 (publication date) through Dec 26, 2024

Times Cited of This Article

Times Cited (1)

Journal Information of This Article

Publication Name

World Journal of Psychiatry

ISSN

2220-3206

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Psychiatry. Jul 19, 2024; 14(7): 1009-1016
Published online Jul 19, 2024. doi: 10.5498/wjp.v14.i7.1009

Table 1 Comparison of basic clinical characteristics

	Subthreshold depression (n = 95)	Control (n = 100)	Statistic	P value
Age (years, mean ± SD)	65.3 ± 10.22	63.6 ± 12.4	0.585	0.561
Gender			χ² = 1.60	0.45
Male, n (%)	56 (58.94)	52 (52.00)
Female, n (%)	39 (41.05)	48 (48.00)
Marriage, n (%)			Fisher’s exact test	0.307
Married	63 (66.32)	50 (50.00)
Single	10 (10.52)	8 (8.00)
Bereft	10 (10.52)	12 (12.00)
Devoice	12 (12.65)	25 (25.00)
Work status, n (%)			χ² = 0.804	0.423
Unemployed	79 (0.84)	80 (80.00)
Employed	16 (0.17)	20 (20.00)
Comorbid chronic disease, n (%)			χ² = 0.795	0.428
Yes	12 (12.65)	10 (10.00)
No	83 (87.36)	90 (90.00)
BMI (kg/m², mean ± SD)	24.23 ± 9.29	23.91 ± 10.22	0.868	0.386
Combined radiotherapy, n (%)			χ² = 2.227	0.028
Yes	33 (35.76)	7 (7.00)
No	62 (65.26)	93 (93.00)
Regular exercise, n (%)			χ² = 2.609	0.010
Yes	12 (12.82)	54 (54.00)
No	83 (87.87)	46 (46.00)

Table 2 Comparison of observational indicators between the two groups

	Subthreshold depression (n = 95)	Control (n = 100)	Statistic	P value
Pain score (score, mean ± SD)	3.98 ± 2.43	1.34 ± 0.2	35.918	0.000
PSQI (score, mean ± SD)	11.0 ± 3.1	9.8 ± 1.8	1.841	0.070
Piper Fatigue Scale score (score, mean ± SD)	7.2 ± 1.6	4.5 ± 1.4	4.410	0.000
Hemoglobin (g/L, mean ± SD)	60.24 ± 12.45	71.19 ± 15.34	1.011	0.000
Albumin (g/L, mean ± SD)	33.98 ± 15.66	34.45 ± 19.46	1.534	0.128
CRP (mg/L, mean ± SD)	8.13 ± 1.55	4.24 ± 1.42	2.832	0.005

PSQI: Pittsburgh Sleep Quality Index; CRP: C-reactive protein.

Table 3 Correlation analysis of Piper Fatigue Scale scores in leukemia patients

	PFS score	Emotion	Recognition	Behavior	Sensation
Age	0.741^a	0.791^a	0.753^a	0.745^a	0.736^a
Pain	0.321	0.561	0.176	0.264	0.146
Hemoglobin	-0.667^a	-0.447	-0.453	-0.681^a	-0.636^a
CRP	0.463^a	0.328^a	0.285	0.339	0.642^a
Regular exercise	0.602^a	0.561^a	0.453	0.456	0.636^a

^aP < 0.05.

PFS: Piper Fatigue Scale; CRP: C-reactive protein.

Table 4 Multivariate regression analysis of piper fatigue scale scores in patients with malignant hematological diseases

	Value	B	SE	β	t value	P value
Age (years)		6.660	2.331	0.062	2.821	0.002^a
Concurrent radiotherapy	(No = 1, Yes = 2)	123.09	69.894	0.042	2.021	0.033^a
Regular exercise	(No = 1, Yes = 2)	-236.85	75.913	-0.068	-3.120	0.002^a
Pain	Score	2.014	0.421	0.102	4.420	< 0.001^a
Hemoglobin		2.825	1.333	0.043	2.081	0.031^a

^aP < 0.05.

Citation: Liu YX, Wang J. Impact of comorbid subthreshold depressive symptoms on cancer-related fatigue and complications in adults with leukemia. World J Psychiatry 2024; 14(7): 1009-1016
URL: https://www.wjgnet.com/2220-3206/full/v14/i7/1009.htm
DOI: https://dx.doi.org/10.5498/wjp.v14.i7.1009