Impact of thoracic paravertebral block and sufentanil on outcomes and postoperative cognitive dysfunction in thoracoscopic lung cancer surgery

Table 1 Comparison of baseline data

Factors		TPVB group (n = 57)	Control group (n = 50)	χ2/t test	P value
Age				0.633	0.426
	≥ 60 years	31	31
	< 60 years	26	19
Sex				0.342	0.558
	Male	31	30
	Female	26	20
Pathological stage				1.219	0.543
	I	17	20
	II	28	21
	III	12	9
Pathological type				0.587	0.443
	Squamous cell carcinoma	27	20
	Adenocarcinoma	30	30
Operation time		147.35 ± 15.70	148.44 ± 13.30	0.384	0.701
Intraoperative blood loss (mL)		141.05 ± 54.49	131.14 ± 53.54	0.946	0.346
History of diabetes				0.679	0.409
	Yes	10	12
	No	47	38
History of hypertension				1.153	0.282
	Yes	14	17
	No	43	33

TPVB: Thoracic paravertebral block.

Table 2 Changes in Mini-Mental State Examination scores

Grouping	Before surgery	3 days after surgery	5 days after surgery
TPVB group (n = 57)	28.51 ± 0.95	25.05 ± 1.20a	27.56 ± 0.95b
Control group (n = 50)	28.06 ± 1.27	23.42 ± 1.31a	27.38 ± 0.85a,b
t value	2.140	7.909	3.402
P value	0.499	< 0.001	0.016

^aP < 0.05 compared with the preoperative level.

^bP < 0.05 compared with the value at 3 days after surgery.

TPVB: Thoracic paravertebral block.

Table 3 Changes in Ramsay sedation scores

Grouping	2 h after surgery	12 h after surgery	24 h after surgery
TPVB group (n = 57)	2.91 ± 0.93	2.91 ± 0.74	2.70 ± 0.50
Control group (n = 50)	2.62 ± 0.64	2.66 ± 0.69	2.62 ± 0.49
t value	2.241	1.946	0.686
P value	0.388	0.791	0.945

TPVB: Thoracic paravertebral block.

Table 4 Visual analog scale score changes

Grouping	2 h after surgery	12 h after surgery	24 h after surgery
TPVB group (n = 57)	3.53 ± 0.6	2.68 ± 0.47a	2.18 ± 0.38a,b
Control group (n = 50)	3.42 ± 0.54	2.98 ± 0.14a	2.5 ± 0.54a,b
t value	1.064	3.318	3.632
P value	0.934	0.015	0.005

^aP < 0.05 compared with the preoperative level.

^bP < 0.05 compared with the value at 12 h after surgery.

TPVB: Thoracic paravertebral block.

Table 5 Statistical analysis of adverse reactions

Grouping	Nausea and vomiting	Hypotension	Delayed recovery from anesthesia	Respiratory depression
TPVB group (n = 57)	2	3	1	0
Control group (n = 50)	1	2	1	2
χ2	0.222	0.095	0.001	2.323
P value	0.637	0.757	0.925	0.127

TPVB: Thoracic paravertebral block.