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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Jun 19, 2024; 14(6): 894-903
Published online Jun 19, 2024. doi: 10.5498/wjp.v14.i6.894
Published online Jun 19, 2024. doi: 10.5498/wjp.v14.i6.894
Impact of thoracic paravertebral block and sufentanil on outcomes and postoperative cognitive dysfunction in thoracoscopic lung cancer surgery
Dan-Dan Wang, Hong-Yu Wang, Yan Zhu, Xi-Hua Lu, Department of Anesthesiology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, Henan Province, China
Author contributions: Wang DD designed the research and wrote the first manuscript; Wang DD, Wang HY, Zhu Y and Lu XH contributed to conceiving the research and analyzing data; Wang DD conducted the analysis and provided guidance for the research; all authors reviewed and approved the final manuscript.
Institutional review board statement: This study was approved by the Ethic Committee of The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: Dr. Lu has nothing to disclose.
Data sharing statement: All data and materials are available from the corresponding author.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xi-Hua Lu, MM, Doctor, Department of Anesthesiology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, No. 127 Dongming Road, Jinshui District, Zhengzhou 450008, Henan Province, China. hnlxh66@163.com
Received: March 12, 2024
Revised: May 13, 2024
Accepted: May 24, 2024
Published online: June 19, 2024
Processing time: 99 Days and 4.4 Hours
Revised: May 13, 2024
Accepted: May 24, 2024
Published online: June 19, 2024
Processing time: 99 Days and 4.4 Hours
Core Tip
Core Tip: This study demonstrates that the combination of thoracic paravertebral block with sufentanil-based multimodal analgesia in patients undergoing thoracoscopic surgery for lung cancer (LC) enhances analgesia and reduces the rate of postoperative cognitive dysfunction. Besides decreasing postsurgical stress responses and various serum biomarker levels, this combination scheme exhibits higher safety, potentially providing a more effective strategy for pain management and cognitive function preservation. Our findings pave the way for new standards in postoperative care for LC surgery.