Mindfulness-based stress reduction training and supplemented Jinshui Liujun decoction promote recovery in patients with non-small cell lung cancer

doi:10.5498/wjp.v14.i12.1876

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Dec 19, 2024; 14(12): 1876-1885
Published online Dec 19, 2024. doi: 10.5498/wjp.v14.i12.1876

Table 1 Baseline data of patients with non-small cell lung cancer

Projects	n	TG (n = 57)	CG (n = 35)	χ²/t	P value
Sex, n (%)				0.009	0.925
Male	61	38 (66.67)	23 (65.71)
Female	31	19 (33.33)	12 (34.29)
Age, mean ± SD		59.77 ± 5.22	60.74 ± 6.18	-0.807	0.422
BMI (kg/m²), mean ± SD		21.44 ± 1.84	21.20 ± 2.00	0.584	0.561
Hypertension history, n (%)				0.001	0.973
Find	13	8 (14.04)	5 (14.29)
Nil	79	49 (85.96)	30 (85.71)
History of diabetes, n (%)				0.074	0.785
Find	7	4 (7.02)	3 (8.57)
Nil	85	53 (92.98)	32 (91.43)
Duration of disease (month), mean ± SD		8.82 ± 6.04	9.00 ± 2.20	-0.389	0.698
Pathological stage, n (%)				0.038	0.981
IIIb	26	16 (28.07)	10 (28.57)
IIIc	52	32 (56.14)	20 (57.14)
IV	14	9 (15.79)	5 (14.29)
Pathological classification, n (%)				0.025	0.988
Adenocarcinoma	43	27 (47.37)	16 (45.71)
Squamous carcinoma	36	22 (38.60)	14 (40.00)
Others	13	8 (14.04)	5 (14.29)
Tumor diameter (cm), mean ± SD		3.14 ± 1.16	3.17 ± 1.13	-0.122	0.903

CG: Control group; TG: Treatment group; BMI: Body mass index.

Table 2 Karnofsky performance status scores

Group	n	KPS scores
Group	n	Before treatment	After treatment
TG	57	50 (40, 60)	60 (40, 70)
CG	35	50 (40, 60)	50 (40, 60)
χ²		0.015	12.394
P value		0.992	0.006

CG: Control group; TG: Treatment group; KPS: Karnofsky performance status.

Table 3 Therapeutic efficacy in the treatment group and control group, n (%)

Group	n	CR	PR	SD	PD	DCR	χ²	P value
TG	57	13 (22.81)	15 (26.32)	13 (22.81)	16 (28.06)	41 (71.94)	3.962	0.047
CG	35	3 (8.57)	5 (14.29)	10 (28.57)	17 (48.57)	18 (51.43)

CR: Complete remission; PR: Partial remission; SD: Stable disease; PD: Progressive disease; DCR: Disease control rate; CG: Control group; TG: Treatment group.

Table 4 Occurrence rate of adverse reactions in the treatment group and control group, n (%)

Group	n	Breathing difficulties	Diarrhea	Vomiting	Proteinuria	Overall response rate	χ²	P value
TG	57	1 (1.75)	2 (3.51)	2 (3.51)	1 (1.75)	6 (10.52)	0.018	0.893
CG	35	1 (2.86)	1 (2.86)	1 (2.86)	1 (2.86)	4 (11.44)

CG: Control group; TG: Treatment group.

Citation: Liu DW, Zhou XA, Wu XY, Wang YX, Fan JT, Li ZL. Mindfulness-based stress reduction training and supplemented Jinshui Liujun decoction promote recovery in patients with non-small cell lung cancer. World J Psychiatry 2024; 14(12): 1876-1885
URL: https://www.wjgnet.com/2220-3206/full/v14/i12/1876.htm
DOI: https://dx.doi.org/10.5498/wjp.v14.i12.1876