Wang YN, Shi MM, Zhang JM. Value of Chuanjin Qinggan decoction in improving the depressive state of patients with herpes zoster combined with depression. World J Psychiatry 2023; 13(12): 1037-1045 [PMID: 38186733 DOI: 10.5498/wjp.v13.i12.1037]
Corresponding Author of This Article
Jin-Ming Zhang, MM, Attending Doctor, Department of Geriatrics, Yantai Traditional Chinese Medicine Hospital, No. 93-1-9 Xingfu Road, Zhifu District, Yantai 264000, Shandong Province, China. zjmyt1987@163.com
Research Domain of This Article
Psychiatry
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
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World J Psychiatry. Dec 19, 2023; 13(12): 1037-1045 Published online Dec 19, 2023. doi: 10.5498/wjp.v13.i12.1037
Table 1 Clinical characteristics of study subjects [n (%)], M (P25, P75)
Clinical characteristics
Western medicine (n = 43)
Combination (n = 43)
χ2/t
P value
Sex
0.427
0.514
Man
26 (60.50)
23 (53.50)
Woman
17 (39.50)
20 (46.50)
Age (yr)
58.53 ± 5.16
59.12 ± 5.04
-0.528
0.599
Herpes zoster disease course (d)
5.00 (4.00, 6.00)
5.00 (4.00, 6.00)
-0.317
0.751
Residence
0.187
0.665
Town
19 (44.20)
21 (48.80)
City
24 (55.80)
22 (51.20)
Years of education
0.466
0.792
< 9
8 (18.60)
10 (23.30)
9-12
24 (55.80)
21 (48.80)
> 12
11 (25.60)
12 (27.90)
Table 2 The pain scores between the two groups, M (P25, P75)
Group
Pre-treatment
Post-treatment
Z
P value
Western medicine (n = 43)
7.00 (6.00, 8.00)
4.00 (4.00, 5.00)
-6.801
< 0.001
Combination (n = 43)
7.00 (6.00, 8.00)
4.00 (3.00, 4.00)
-7.960
< 0.001
Z
-0.448
-3.825
P value
0.654
< 0.001
Table 3 Effectiveness of herpes zoster treatment, n (%)
Group
Remarkable effect
Effective
Ineffective
Western medicine (n = 43)
11 (25.58)
22 (51.16)
10 (23.26)
Combination (n = 43)
19 (44.19)
18 (41.86)
6 (13.95)
Z
-2.144
P value
0.032
Table 4 Comparison of adverse reactions produced by different treatment regimens, n (%)
Group
Headache
Blurred vision
Nausea
Emesis
Others
Total
Western medicine (n = 43)
5 (11.63)
2 (4.65)
6 (13.95)
3 (6.98)
3 (6.98)
17 (39.53)
Combination (n = 43)
2 (4.65)
1 (2.33)
4 (9.30)
1 (2.33)
3 (6.98)
8 (18.60)
χ2
4.568
P value
0.033
Citation: Wang YN, Shi MM, Zhang JM. Value of Chuanjin Qinggan decoction in improving the depressive state of patients with herpes zoster combined with depression. World J Psychiatry 2023; 13(12): 1037-1045