Wang YN, Shi MM, Zhang JM. Value of Chuanjin Qinggan decoction in improving the depressive state of patients with herpes zoster combined with depression. World J Psychiatry 2023; 13(12): 1037-1045 [PMID: 38186733 DOI: 10.5498/wjp.v13.i12.1037]
Corresponding Author of This Article
Jin-Ming Zhang, MM, Attending Doctor, Department of Geriatrics, Yantai Traditional Chinese Medicine Hospital, No. 93-1-9 Xingfu Road, Zhifu District, Yantai 264000, Shandong Province, China. zjmyt1987@163.com
Research Domain of This Article
Psychiatry
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. Dec 19, 2023; 13(12): 1037-1045 Published online Dec 19, 2023. doi: 10.5498/wjp.v13.i12.1037
Value of Chuanjin Qinggan decoction in improving the depressive state of patients with herpes zoster combined with depression
Yi-Nan Wang, Meng-Meng Shi, Jin-Ming Zhang
Yi-Nan Wang, Department of Dermatology, Yantai Hospital of Traditional Chinese Medicine, Yantai 264000, Shandong Province, China
Meng-Meng Shi, Jin-Ming Zhang, Department of Geriatrics, Yantai Traditional Chinese Medicine Hospital, Yantai 264000, Shandong Province, China
Co-first authors: Yi-Nan Wang and Meng-Meng Shi.
Author contributions: This paper was written by Wang YN, Shi MM, and Zhang JM; Wang YN led the writing of the article; Zhang JM proofread all drafts; and Shi MM, the director of the paper, provided the first guidance; all authors contributed to revision of this paper and made constructive suggestions to ensure accurate expression of the research results. Wang YN and Shi MM contributed equally to this work and are co-first authors.
Institutional review board statement: This study was reviewed and approved by Yantai Hospital of Traditional Chinese Medicine.
Informed consent statement: This retrospective study was exempt from the requirement of informed consent according to institutional policies.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: The data used in this study can be obtained from the corresponding author upon request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin-Ming Zhang, MM, Attending Doctor, Department of Geriatrics, Yantai Traditional Chinese Medicine Hospital, No. 93-1-9 Xingfu Road, Zhifu District, Yantai 264000, Shandong Province, China. zjmyt1987@163.com
Received: September 12, 2023 Peer-review started: September 12, 2023 First decision: September 25, 2023 Revised: October 12, 2023 Accepted: November 16, 2023 Article in press: November 16, 2023 Published online: December 19, 2023 Processing time: 98 Days and 3.8 Hours
ARTICLE HIGHLIGHTS
Research background
The physical and mental suffering of patients with herpes zoster combined with depression is significant. Although traditional Western medicine can alleviate the depressive symptoms in patients to a certain extent, it also causes many adverse reactions. There remains a need to identify drugs with high clinical safety that can effectively improve the depressive symptoms in patients with herpes zoster combined with depression.
Research motivation
To search for safe drugs that can effectively improve the depressive symptoms of patients with herpes zoster combined with depression, and to provide references for the formulation and modification of the treatment plan for herpes zoster combined with depression.
Research objectives
We analyzed the value of Chuanjin Qinggan decoction combined with a serotonin- selective reuptake inhibitor in the treatment of patients with herpes zoster complicated by depression.
Research methods
We retrospectively analyzed depression status, treatment effect, degree of pain, neurotransmitter levels, sleep quality, and adverse reactions in patients with herpes zoster complicated by depression who received different treatment schemes.
Research results
Compared with patients treated with selective serotonin reuptake inhibitor (SSRIs) alone, patients treated with Chuanjin Qinggan decoction combined with SSRIs showed a greater improvement in depression after treatment, and the incidence of adverse reactions was lower.
Research conclusions
The treatment scheme of the Chuanjin Qinggan decoction combined with SSRIs can improve the depressive state of patients with herpes zoster complicated by depression, and improve the effect of treatment for herpes zoster without increasing the risk of adverse reactions.
Research perspectives
In the future, the specific mechanism of Chuanjin Qinggan decoction in the treatment of herpes zoster complicated by depression should be clarified through cell or animal experiments, to provide references for further improving the therapeutic effect.
