Retrospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatr. Mar 22, 2015; 5(1): 126-137
Published online Mar 22, 2015. doi: 10.5498/wjp.v5.i1.126
Mood Spectrum Model: Evidence reconsidered in the light of DSM-5
Antonella Benvenuti, Mario Miniati, Antonio Callari, Michela Giorgi Mariani, Mauro Mauri, Liliana Dell’Osso
Antonella Benvenuti, Mario Miniati, Antonio Callari, Michela Giorgi Mariani, Mauro Mauri, Liliana Dell’Osso, Department of Clinical and Experimental Medicine, University of Pisa, 56100 Pisa, Italy
Author contributions: All authors provided substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data; contributions to drafting the article or revising it critically for important intellectual content; and approved to the final version to be published.
Ethics approval: No basic research, clinical researches or case reports have been performed for this paper. All data are available and already published in international peer-reviewed journals. No additional analyses were performed. No meta-analyses were conducted. No databases were requested to the authors of the reviewed papers.
Informed consent: No new clinical researches or case reports involving humans were performed for this paper. All reviewed studies were already published after the approvals of informed consents and ethical issues, when appropriate.
Conflict-of-interest: None.
Data sharing: No basic research and clinical research studies that require a data sharing statement were performed for this paper. All data derived from already published papers.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Antonella Benvenuti, MD, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56100 Pisa, Italy. antonellabenvenuti@virgilio.it
Telephone: +39-050-999616 Fax: +39-050-2219787
Received: September 27, 2014
Peer-review started: September 28, 2014
First decision: November 19, 2014
Revised: January 7, 2015
Accepted: January 18, 2015
Article in press: January 20, 2015
Published online: March 22, 2015
Processing time: 176 Days and 23 Hours
Core Tip

Core tip: Data emerging from the proposed mood spectrum approach suggest the existence of a continuum from “pure mania” to “pure depression”, without a clear cut-off between the two realms. As a whole, the experience with the mood spectrum model enforces past and recent claims towards the need for a unitary dimensional approach to mood disorders.