Research progress of postoperative delirium in neurosurgery

doi:10.5498/wjp.v15.i4.104708

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Apr 19, 2025 (publication date) through Mar 25, 2025

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Apr 19, 2025; 15(4): 104708
Published online Apr 19, 2025. doi: 10.5498/wjp.v15.i4.104708

Research progress of postoperative delirium in neurosurgery

Xue-Jian Wang

Xue-Jian Wang, Department of Neurosurgery, Affiliated Hospital 2 of Nantong University, Nantong 226000, Jiangsu Province, China

Author contributions: Wang XJ wrote and revised this manuscript, and formatted the manuscript.

Supported by Science and Technology Program of Nantong City, No. Key003; Nantong Young Medical Expert, No. 46; the Science and Technology Program of Nantong Health Committee, No. MA2019003, No. MA2021017, and No. MSZ2024038; Science and Technology Program of Nantong City, No. JCZ2022040; and Kangda College of Nanjing Medical University, No. KD2021JYYJYB025, No. KD2022KYJJZD022, and No. KD2024KYJJ289.

Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Xue-Jian Wang, MD, PhD, Department of Neurosurgery, Affiliated Hospital 2 of Nantong University, No. 666 Shengli Road, Chongchuan District, Nantong 226000, Jiangsu Province, China. 6841441@163.com

Received: December 29, 2024
Revised: January 25, 2025
Accepted: March 7, 2025
Published online: April 19, 2025
Processing time: 86 Days and 9.4 Hours

Core Tip

Core Tip: Delirium is an acute neurological dysfunction marked by confusion, disorientation, and disturbances in sensory perception, cognition, and emotional regulation, often accompanied by hallucinations and delusions. Patients may also exhibit psychomotor agitation and heightened anxiety. Postoperative delirium is particularly prevalent among elderly individuals, posing a significant challenge in clinical settings. This review aims to provide a comprehensive analysis of the definition, diagnostic approaches, pathological mechanisms, and associated risk factors of postoperative delirium in neurosurgical patients, offering valuable insights to enhance clinical diagnosis and treatment strategies.