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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Apr 19, 2025; 15(4): 103827
Published online Apr 19, 2025. doi: 10.5498/wjp.v15.i4.103827
Published online Apr 19, 2025. doi: 10.5498/wjp.v15.i4.103827
Effects of exercise-cognitive dual-task training on elderly patients with cognitive frailty and depression
Ying Zhou, Cheng-Ji Yu, Ping Lu, Juan Zhao, Department of Nursing, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Ying Zhou, Cheng-Ji Yu, Ping Lu, Juan Zhao, Department of Nursing, Zhejiang University School of Medicine, Hangzhou 310000, Zhejiang Province, China
Xiao-Ming Miao, Acupuncture and Rehabilitation Center, Tongxiang Hospital of Traditional Chinese Medicine, Tongxiang 314599, Zhejiang Province, China
Kai-Lian Zhou, Department of Nursing, The First Affiliated Hospital of Jiaxing University, Jiaxing 314299, Zhejiang Province, China
Yin Lu, Department of Rehabilitation, Affiliated Rehabilitation Hospital of Tongxiang Health School, Tongxiang 314599, Zhejiang Province, China
Co-first authors: Ying Zhou and Xiao-Ming Miao.
Author contributions: Zhou Y and Miao XM conceived and designed the study, developed the intervention protocol, collected and analyzed data, and drafted the manuscript; Zhou KL and Lu Y assisted in data collection, analysis, and manuscript preparation; Yu CJ provided statistical guidance and contributed to data interpretation; Lu P offered clinical resources and reviewed the manuscript for critical intellectual content; Zhao J supervised the research process and approved the final manuscript; All authors reviewed and approved the final version.
Institutional review board statement: This study was conducted in accordance with the Declaration of Helsinki and approved by the Ethics Committee of the Second Affiliated Hospital of Zhejiang University (Approval No. 2024 Research Ethics Review No. 0567).
Informed consent statement: This study was a retrospective analysis of previously collected data. The requirement for informed consent was waived by the Ethics Committee of the Second Affiliated Hospital of Zhejiang University (Approval No. 2024 Research Ethics Review No. 0567) due to the retrospective nature of the study and the use of anonymized data.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: The data that support the findings of this study are available from the corresponding author upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ying Zhou, MD, Department of Nursing, The Second Affiliated Hospital of Zhejiang University School of Medicine, No. 88 Jiefang Road, Shangcheng District, Hangzhou 310009, Zhejiang Province, China. antareszhou@163.com
Received: December 13, 2024
Revised: January 20, 2025
Accepted: February 21, 2025
Published online: April 19, 2025
Processing time: 102 Days and 0.3 Hours
Revised: January 20, 2025
Accepted: February 21, 2025
Published online: April 19, 2025
Processing time: 102 Days and 0.3 Hours
Core Tip
Core Tip: This study demonstrates that exercise-cognitive dual-task training significantly improves frailty, cognitive function, psychological well-being, and quality of life in elderly patients with cognitive frailty and depression. The intervention combines physical exercises and cognitive tasks, enhancing neuroplasticity and optimizing cognitive-motor integration. Results revealed lower frailty and depression scores and higher cognitive, balance, and quality of life scores in the observation group compared to the control group. These findings underscore the importance of multimodal interventions in geriatric care to mitigate the adverse effects of aging-related cognitive and psychological conditions. Long-term implementation could potentially delay or reverse cognitive frailty progression.