Xu Q, Lu SR, Shi ZH, Yang Y, Yu J, Wang Z, Zhang BS, Hong K. Nutritional status of elderly hypertensive patients and its relation to the occurrence of cognitive impairment. World J Psychiatry 2025; 15(4): 103092 [DOI: 10.5498/wjp.v15.i4.103092]
Corresponding Author of This Article
Kan Hong, PhD, Chief Physician, Department of Geriatrics, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi Medical Center, Nanjing Medical University, Wuxi People’s Hospital, No. 299 Qingyang Road, Wuxi 214023, Jiangsu Province, China. hongkan163@163.com
Research Domain of This Article
Gerontology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. Apr 19, 2025; 15(4): 103092 Published online Apr 19, 2025. doi: 10.5498/wjp.v15.i4.103092
Nutritional status of elderly hypertensive patients and its relation to the occurrence of cognitive impairment
Qiao Xu, Shou-Rong Lu, Zi-Hao Shi, Ying Yang, Jie Yu, Zhuo Wang, Bing-Shan Zhang, Kan Hong
Qiao Xu, Shou-Rong Lu, Ying Yang, Jie Yu, Zhuo Wang, Bing-Shan Zhang, Kan Hong, Department of Geriatrics, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi Medical Center, Nanjing Medical University, Wuxi People’s Hospital, Wuxi 214023, Jiangsu Province, China
Zi-Hao Shi, Department of Clinical Nutrition, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi Medical Center, Nanjing Medical University, Wuxi People’s Hospital, Wuxi 214023, Jiangsu Province, China
Author contributions: Shi ZH was the guarantor and designed the study; Wang Z and Zhang BS participated in the acquisition, analysis, interpretation of the data, and drafted the initial manuscript; Xu Q and Yang Y revised the article critically for important intellectual content; Xu Q, Lu SR, Shi ZH, Yang Y, Yu J, Wang Z, Zhang BS, and Hong K contributed to the article and approved the submitted version.
Supported by the Wuxi Science and Technology Plan Project Plan, No. BJ21008.
Institutional review board statement: The study was reviewed and approved by the Wuxi people’s hospital Medical Ethics Committee.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement:sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kan Hong, PhD, Chief Physician, Department of Geriatrics, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi Medical Center, Nanjing Medical University, Wuxi People’s Hospital, No. 299 Qingyang Road, Wuxi 214023, Jiangsu Province, China. hongkan163@163.com
Received: December 13, 2024 Revised: January 12, 2025 Accepted: February 13, 2025 Published online: April 19, 2025 Processing time: 102 Days and 0.5 Hours
Core Tip
Core Tip: In summary, this study investigated the relationship between nutritional status and cognitive function in elderly hypertensive patients. By retrospectively analyzing data from 200 patients admitted for hypertension, the study divided them into modeling and validation cohorts, and further categorized them based on Mini-Nutritional Assessment Scale and Montreal Cognitive Assessment Scale (MoCA) scores. The results indicated that body mass index, Mini-Nutritional Assessment Scale score, hemoglobin, and albumin were independent protective factors for cognitive impairment, positively correlated with MoCA scores, while alkaline phosphatase was an independent risk factor, negatively correlated with MoCA scores. A predictive nomogram model for cognitive impairment was constructed and validated, exhibiting strong predictive accuracy and consistency in aligning predicted with actual events.
