Liu YF, Cong W, Zhou CM, Yu Y, Zhang XJ. Relationship between inflammatory factors, lactic acid levels, acute skin failure, bad mood, and sleep quality. World J Psychiatry 2025; 15(4): 102763 [DOI: 10.5498/wjp.v15.i4.102763]
Corresponding Author of This Article
Xin-Jie Zhang, Department of Intensive Care Medicine, The Second Hospital of Dalian Medical University, No. 467 Zhongshan Road, Shahekou District, Dalian 116027, Liaoning Province, China. 17709870978@163.com
Research Domain of This Article
Psychiatry
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. Apr 19, 2025; 15(4): 102763 Published online Apr 19, 2025. doi: 10.5498/wjp.v15.i4.102763
Relationship between inflammatory factors, lactic acid levels, acute skin failure, bad mood, and sleep quality
Yu-Fei Liu, Wen Cong, Chang-Ming Zhou, Yang Yu, Xin-Jie Zhang
Yu-Fei Liu, Chang-Ming Zhou, Department of Emergency Critical Care Medicine, The Second Hospital of Dalian Medical University, Dalian 116027, Liaoning Province, China
Wen Cong, Department of Psychiatry, Dalian Seventh People’s Hospital (Dalian Mental Health Center), Dalian 116023, Liaoning Province, China
Yang Yu, Xin-Jie Zhang, Department of Intensive Care Medicine, The Second Hospital of Dalian Medical University, Dalian 116027, Liaoning Province, China
Author contributions: Liu YF designed and performed the research and wrote the paper; Cong W and Zhang XJ designed the research and critical revision; Zhou CM and Yu Y acquired, analyzed, and interpreted the data. All authors approved this study.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of the Second Hospital of Dalian Medical University, No. KY2024-228-01.
Informed consent statement: All study participants or their legal guardians provided written informed consent for the collection of personal and medical data before study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The datasets are available from the corresponding author. Participants provided informed consent for data sharing.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xin-Jie Zhang, Department of Intensive Care Medicine, The Second Hospital of Dalian Medical University, No. 467 Zhongshan Road, Shahekou District, Dalian 116027, Liaoning Province, China. 17709870978@163.com
Received: November 21, 2024 Revised: December 26, 2024 Accepted: February 8, 2025 Published online: April 19, 2025 Processing time: 124 Days and 1.8 Hours
Core Tip
Core Tip: The pathological changes in acute skin failure (ASF) include acute skin hypoperfusion caused by hemodynamic instability in critically ill patients. Systemic inflammatory response syndrome permeates the entire pathological mechanism of septic shock complicated by ASF, and the relevant blood indices can reflect changes in ASF. Bad mood and sleep disturbances are common accompanying symptoms in patients with sepsis, which significantly impact their overall health. Through this project, we found that the levels of peripheral blood-related inflammatory factors and lactic acid were positively correlated with skin mottling score, self-rating anxiety scale, self-rating depression scale, and Pittsburgh sleep quality index scores in critically ill patients with ASF.
