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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Apr 19, 2025; 15(4): 100650
Published online Apr 19, 2025. doi: 10.5498/wjp.v15.i4.100650
Published online Apr 19, 2025. doi: 10.5498/wjp.v15.i4.100650
Social and obstetric risk factors of antenatal depression: A cross-sectional study in China
Zi-Ping He, Mi Wang, Department of Mental Health Center, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China
Zi-Ping He, Jun-Zhe Cheng, Yu-Bo Wang, Chen-Kun Wu, Xiangya School of Medicine, Central South University, Changsha 410013, Hunan Province, China
Jun-Zhe Cheng, Yu-Bo Wang, Zhi-Xuan Ren, Yi-Lin Peng, Jin-Tao Xiong, Xue-Mei Qin, Zhuo Peng, Wei-Guo Mao, Li Zhang, Yu-Meng Ju, Jin Liu, Bang-Shan Liu, Yan Zhang, Department of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan Province, China
Yan Yu, Ming-Fang Chen, Department of Obstetrics, Baoan Maternal and Child Health Care Hospital, Shenzhen 518100, Guangdong Province, China
Co-first authors: Zi-Ping He and Jun-Zhe Cheng.
Co-corresponding authors: Mi Wang and Yan Zhang.
Author contributions: He ZP and Cheng JZ contribute equally to this study as co-first authors; Wang M and Zhang Y contribute equally to this study as co-corresponding authors; Zhang Y, Yu Y, and Wang M were responsible for the organization and coordination of the trial; Cheng JZ, He ZP, and Liu BS were the chief investigators and responsible for the data analysis; Cheng JZ, and Liu BS developed the trial design; all authors contributed to the management or administration of the trial and the writing and reviewing of the final manuscript.
Supported by the Joint Funds of the National Natural Science Foundation of China, No. U23A20434; National Natural Science Foundation of China, No. 82301738, No. 82371535, and No. 82171518; the National Key Research and Development Program of China, No. 2021YFF1201204; and the Science and Technology Innovation Program of Hunan Province, No. 2023RC3083.
Institutional review board statement: This study was approved by the ethics committee of Shenzhen Baoan Women’s and Children’s Hospital (approval number: LLSC-2023-03-11-11-KS).
Informed consent statement: All the eligible participants provided written informed consent according to the research protocol.
Conflict-of-interest statement: The authors have no conflicts to disclose.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Data sharing statement: The original contributions presented in the study are included in the article/Supplementary material, further inquiries can be directed to the corresponding author.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mi Wang, MD, Doctor, Department of Mental Health Center, Xiangya Hospital of Central South University, No. 87 Xiangya Road, Changsha 410008, Hunan Province, China. mi.wang@csu.edu.cn
Received: August 23, 2024
Revised: January 1, 2025
Accepted: February 7, 2025
Published online: April 19, 2025
Processing time: 214 Days and 2.6 Hours
Revised: January 1, 2025
Accepted: February 7, 2025
Published online: April 19, 2025
Processing time: 214 Days and 2.6 Hours
Core Tip
Core Tip: The present study aimed to assess the sociodemographic and obstetric factors of antenatal depression based on a large Chinese population. This study suggested that the prevalence of antenatal depression was 4.4%. Several social and obstetric factors were identified as risk factors for antenatal depression. Edinburgh Postnatal Depression Scale (EPDS)8 ("sad or miserable") and EPDS4 ("anxious or worried") are pivotal targets for clinical intervention to alleviate the burden of antenatal depression. It is expected that this study can facilitate psychological intervention of women in early pregnancy, reduce the risk of prenatal depression, and mitigate the adverse impact of risk factors. Early identification of high-risk groups is crucial for the development and implementation of intervention strategies to improve the overall quality of life for pregnant women.